Literature DB >> 9665161

New insights into heparin-induced FGF oligomerization.

G Waksman, A B Herr.   

Abstract

Fibroblast growth factors (FGFs) play important roles in a variety of developmental processes in mammals. The dependence of their activity on heparin binding has been a puzzle that, in recent years, has been the subject of active investigation. Recent structural analyses on complexes of FGFs with heparin fragments or heparin analogs have unveiled the extreme complexity of these systems.

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Year:  1998        PMID： 9665161     DOI： 10.1038/778

Source DB:  PubMed          Journal:  Nat Struct Biol        ISSN： 1072-8368


  15 in total

1.  So what do your sugars do?

Authors:  R C Hughes
Journal:  Glycoconj J       Date:  2000 Jul-Sep       Impact factor: 2.916

2.  Oligomerization of acidic fibroblast growth factor is not a prerequisite for its cell proliferation activity.

Authors:  Alphonse I Arunkumar; Thallampuranam Krishnaswamy S Kumar; Karuppanan Muthusamy Kathir; Sampath Srisailam; Han-Min Wang; Philominathan Sagaya Theresa Leena; Ya-Hui Chi; Ho-Chz Chen; Chieh-Hsi Wu; Rong-Tsun Wu; Gu-Gang Chang; Ing-Ming Chiu; Chin Yu
Journal:  Protein Sci       Date:  2002-05       Impact factor: 6.725

3.  Fibroblast growth factor 2 dimer with superagonist in vitro activity improves granulation tissue formation during wound healing.

Authors:  Caitlin G Decker; Yu Wang; Samantha J Paluck; Lu Shen; Joseph A Loo; Alex J Levine; Lloyd S Miller; Heather D Maynard
Journal:  Biomaterials       Date:  2015-12-15       Impact factor: 12.479

4.  Structure Activity Relationship of Heparin Mimicking Polymer p(SS-co-PEGMA): Effect of Sulfonation and Polymer Size on FGF2-Receptor Binding.

Authors:  Samantha J Paluck; Heather D Maynard
Journal:  Polym Chem       Date:  2017-07-05       Impact factor: 5.582

5.  Structure and response to flow of the glycocalyx layer.

Authors:  Eduardo R Cruz-Chu; Alexander Malafeev; Tautrimas Pajarskas; Igor V Pivkin; Petros Koumoutsakos
Journal:  Biophys J       Date:  2014-01-07       Impact factor: 4.033

6.  Backbone dynamics of a biologically active human FGF-1 monomer, complexed to a hexasaccharide heparin-analogue, by 15N NMR relaxation methods.

Authors:  Angeles Canales-Mayordomo; Rosa Fayos; Jesús Angulo; Rafael Ojeda; Manuel Martín-Pastor; Pedro M Nieto; Manuel Martín-Lomas; Rosa Lozano; Guillermo Giménez-Gallego; Jesús Jiménez-Barbero
Journal:  J Biomol NMR       Date:  2006-07-29       Impact factor: 2.835

7.  Fibroblast growth factors 1 and 2 are distinct in oligomerization in the presence of heparin-like glycosaminoglycans.

Authors:  G Venkataraman; Z Shriver; J C Davis; R Sasisekharan
Journal:  Proc Natl Acad Sci U S A       Date:  1999-03-02       Impact factor: 11.205

8.  Gas-Phase Analysis of the Complex of Fibroblast GrowthFactor 1 with Heparan Sulfate: A Traveling Wave Ion Mobility Spectrometry (TWIMS) and Molecular Modeling Study.

Authors:  Yuejie Zhao; Arunima Singh; Yongmei Xu; Chengli Zong; Fuming Zhang; Geert-Jan Boons; Jian Liu; Robert J Linhardt; Robert J Woods; I Jonathan Amster
Journal:  J Am Soc Mass Spectrom       Date:  2016-09-23       Impact factor: 3.109

9.  Heparin increases prolactin and modifies the effects of fgf-2 upon prolactin accumulation in pituitary primary cultures.

Authors:  Carlos Spuch; Yolanda Diz-Chaves; Diego Pérez-Tilve; Federico Mallo
Journal:  Endocrine       Date:  2004-07       Impact factor: 3.633

10.  Increased protein stability of FGF1 can compensate for its reduced affinity for heparin.

Authors:  Malgorzata Zakrzewska; Antoni Wiedlocha; Anna Szlachcic; Daniel Krowarsch; Jacek Otlewski; Sjur Olsnes
Journal:  J Biol Chem       Date:  2009-07-02       Impact factor: 5.157
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