Literature DB >> 9661737

Round-off error, blind faith, and the powers that be: a caution on numerical error in coefficients for polynomial curves fit to psychophysical data.

V J Samar1, C L De Filippo.   

Abstract

Graphing and statistics software often permits users to fit polynomial curves, like a parabola or sigmoid, to scatter plots of psychophysical data points. These programs typically calculate the curve using double- or extended-precision numerical algorithms and display the resulting curve overlaid graphically on the scatter plot, but they may simultaneously display the equation that generates that curve with numerical coefficients that have been rounded off to only a few decimal places. If this equation is used for experimental or clinical applications, the round-off error, especially on coefficients for the higher powers, can produce anomalous findings due to systematic and extreme distortions of the fitted curve, even artifactually reversing the algebraic sign of the true slope of the fitted curve at particular data points. Care must be exercised in setting round-off criteria for coefficients of polynomial terms in curve-fit equations to avoid nonsensical measurement and prediction.

Entities:  

Mesh:

Year:  1998        PMID: 9661737

Source DB:  PubMed          Journal:  J Outcome Meas        ISSN: 1090-655X


  1 in total

1.  Evaluation of absolute quantitation by nonlinear regression in probe-based real-time PCR.

Authors:  Rasmus Goll; Trine Olsen; Guanglin Cui; Jon Florholmen
Journal:  BMC Bioinformatics       Date:  2006-03-03       Impact factor: 3.169

  1 in total

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