| Literature DB >> 9660840 |
S G Balch1, A J McKnight, M F Seldin, S Gordon.
Abstract
We report the cloning of a novel macrophage-restricted C-type lectin by differential display polymerase chain reaction. This molecule, named mouse macrophage C-type lectin, is a 219-amino acid, type II transmembrane protein with a single extracellular C-type lectin domain. Northern blot analysis indicates that it is expressed in cell lines and normal mouse tissues in a macrophage-restricted manner. The cDNA and genomic sequences of mouse macrophage C-type lectin indicate that it is related to the Group II animal C-type lectins. The mcl gene locus has been mapped between the genes for the interleukin-17 receptor and CD4 on mouse chromosome 6, the same chromosome as the mouse natural killer cell gene complex.Entities:
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Year: 1998 PMID: 9660840 DOI: 10.1074/jbc.273.29.18656
Source DB: PubMed Journal: J Biol Chem ISSN: 0021-9258 Impact factor: 5.157