| Literature DB >> 9659324 |
S J Dalton1, M R Haeney, L Patel, T J David.
Abstract
In two children with atopic dermatitis, routine vaccination with bacillus Calmette-Guérin (BCG) was followed by severe exacerbation of skin disease. If the sequence is cause and effect, a possible mechanism is stimulation of a Th2 lymphocyte cytokine profile by the vaccine, with migration of activated lymphocytes to inflamed skin. In children with active atopic dermatitis, BCG vaccination is best deferred until remission.Entities:
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Year: 1998 PMID： 9659324 PMCID： PMC1296561 DOI： 10.1177/014107689809100305
Source DB: PubMed Journal: J R Soc Med ISSN： 0141-0768 Impact factor: 5.344