Literature DB >> 9658738

Enzyme replacement therapy decreases hypergammaglobulinemia in Gaucher's disease.

J Deibener, P Kaminsky, C Jacob, B Dousset, M Klein, M Duc.   

Abstract

We report the effects of enzyme replacement therapy in a patient with Gaucher's disease associated with a monoclonal gammopathy. Alglucerase induces a linear decline in immunoglobulin and beta 2-microglobulin levels. This observation suggests that this treatment decreases the chronic antigenic stimulation commonly found in Gaucher's disease.

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Year:  1998        PMID： 9658738

Source DB:  PubMed          Journal:  Haematologica        ISSN： 0390-6078            Impact factor:   9.941


  4 in total

1.  IgM monoclonal component associated with type I Gaucher disease resolved after enzyme replacement therapy: a case report.

Authors:  C Martinez-Redondo; F J Ortuño; M L Lozano; A Jerez; M del Mar Osma; P Giraldo; V Vicente
Journal:  J Inherit Metab Dis       Date:  2009-06-27       Impact factor: 4.982

2.  Once again, rare diseases provide a spotlight.

Authors:  Tamanna Roshan Lal; Daniel K Borger; Ellen Sidransky
Journal:  Mol Genet Metab       Date:  2016-03-05       Impact factor: 4.797

3.  Serum β2-microglobulin is frequently elevated in type 1 Gaucher patients.

Authors:  Tiago Koppe; Filippo Vairo; Matheus Camargo; Livia Paskulin; Liane Daudt; Ida V Schwartz
Journal:  Mol Genet Metab Rep       Date:  2014-12-15

4.  Immunoglobulin and free light chain abnormalities in Gaucher disease type I: data from an adult cohort of 63 patients and review of the literature.

Authors:  M de Fost; T A Out; F A de Wilde; E P M Tjin; S T Pals; M H J van Oers; R G Boot; J F M G Aerts; M Maas; S Vom Dahl; C E M Hollak
Journal:  Ann Hematol       Date:  2008-02-15       Impact factor: 3.673
  4 in total

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