Literature DB >> 9658147

Antigenic structure of human respiratory syncytial virus fusion glycoprotein.

J A López1, R Bustos, C Orvell, M Berois, J Arbiza, B García-Barreno, J A Melero.   

Abstract

New series of escape mutants of human respiratory syncytial virus were prepared with monoclonal antibodies specific for the fusion (F) protein. Sequence changes selected in the escape mutants identified two new antigenic sites (V and VI) recognized by neutralizing antibodies and a group-specific site (I) in the F1 chain of the F molecule. The new epitopes, and previously identified antigenic sites, were incorporated into a refined prediction of secondary-structure motifs to generate a detailed antigenic map of the F glycoprotein.

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Year:  1998        PMID： 9658147      PMCID： PMC109907     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  44 in total

1.  Characterization of two antigenic sites recognized by neutralizing monoclonal antibodies directed against the fusion glycoprotein of human respiratory syncytial virus.

Authors:  J Arbiza; G Taylor; J A López; J Furze; S Wyld; P Whyte; E J Stott; G Wertz; W Sullender; M Trudel
Journal:  J Gen Virol       Date:  1992-09       Impact factor: 3.891

2.  Sequence analysis of the gene encoding the fusion glycoprotein of pneumonia virus of mice suggests possible conserved secondary structure elements in paramyxovirus fusion glycoproteins.

Authors:  P Chambers; C R Pringle; A J Easton
Journal:  J Gen Virol       Date:  1992-07       Impact factor: 3.891

3.  Preparation and characterization of monoclonal antibodies directed against five structural components of human respiratory syncytial virus subgroup B.

Authors:  C Orvell; E Norrby; M A Mufson
Journal:  J Gen Virol       Date:  1987-12       Impact factor: 3.891

4.  Structural analysis based on state-space modeling.

Authors:  C M Stultz; J V White; T F Smith
Journal:  Protein Sci       Date:  1993-03       Impact factor: 6.725

Review 5.  Paramyxovirus fusion: a hypothesis for changes.

Authors:  R A Lamb
Journal:  Virology       Date:  1993-11       Impact factor: 3.616

6.  A spring-loaded mechanism for the conformational change of influenza hemagglutinin.

Authors:  C M Carr; P S Kim
Journal:  Cell       Date:  1993-05-21       Impact factor: 41.582

7.  Expression of the F glycoprotein gene from human respiratory syncytial virus in Escherichia coli: mapping of a fusion inhibiting epitope.

Authors:  A Martin-Gallardo; K A Fien; B T Hu; J F Farley; R Seid; P L Collins; S W Hildreth; P R Paradiso
Journal:  Virology       Date:  1991-09       Impact factor: 3.616

8.  Structure and sequence comparison of bovine respiratory syncytial virus fusion protein.

Authors:  M K Pastey; S K Samal
Journal:  Virus Res       Date:  1993-08       Impact factor: 3.303

9.  Conformational constraints of conserved neutralizing epitopes from a major antigenic area of human respiratory syncytial virus fusion glycoprotein.

Authors:  J A López; D Andreu; C Carreño; P Whyte; G Taylor; J A Melero
Journal:  J Gen Virol       Date:  1993-12       Impact factor: 3.891

10.  Assignment of disulfide bridges in the fusion glycoprotein of Sendai virus.

Authors:  S Iwata; A C Schmidt; K Titani; M Suzuki; H Kido; B Gotoh; M Hamaguchi; Y Nagai
Journal:  J Virol       Date:  1994-05       Impact factor: 5.103
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  51 in total

1.  Neutralization of human respiratory syncytial virus infectivity by antibodies and low-molecular-weight compounds targeted against the fusion glycoprotein.

Authors:  Margarita Magro; David Andreu; Paulino Gómez-Puertas; José A Melero; Concepción Palomo
Journal:  J Virol       Date:  2010-06-09       Impact factor: 5.103

2.  Antibody response to the central unglycosylated region of the respiratory syncytial virus attachment protein in mice.

Authors:  Yoshihiko Murata; Seana C Catherman
Journal:  Vaccine       Date:  2012-06-19       Impact factor: 3.641

Review 3.  Neutralizing epitopes on the respiratory syncytial virus fusion glycoprotein.

Authors:  Jason S McLellan
Journal:  Curr Opin Virol       Date:  2015-03-26       Impact factor: 7.090

4.  Structure of respiratory syncytial virus fusion glycoprotein in the postfusion conformation reveals preservation of neutralizing epitopes.

Authors:  Jason S McLellan; Yongping Yang; Barney S Graham; Peter D Kwong
Journal:  J Virol       Date:  2011-05-25       Impact factor: 5.103

5.  Amino acid variation within the fusion protein of respiratory syncytial virus subtype A and B strains during annual epidemics in South Africa.

Authors:  Elizabeth Agenbach; Caroline T Tiemessen; Marietjie Venter
Journal:  Virus Genes       Date:  2005-03       Impact factor: 2.332

6.  A vulnerable, membrane-proximal site in human respiratory syncytial virus F revealed by a prefusion-specific single-domain antibody.

Authors:  Iebe Rossey; Ching-Lin Hsieh; Koen Sedeyn; Marlies Ballegeer; Bert Schepens; Jason S Mclellan; Xavier Saelens
Journal:  J Virol       Date:  2021-03-10       Impact factor: 5.103

Review 7.  Animal pneumoviruses: molecular genetics and pathogenesis.

Authors:  Andrew J Easton; Joseph B Domachowske; Helene F Rosenberg
Journal:  Clin Microbiol Rev       Date:  2004-04       Impact factor: 26.132

Review 8.  Structural, antigenic and immunogenic features of respiratory syncytial virus glycoproteins relevant for vaccine development.

Authors:  José A Melero; Vicente Mas; Jason S McLellan
Journal:  Vaccine       Date:  2016-09-28       Impact factor: 3.641

9.  Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody.

Authors:  Jason S McLellan; Man Chen; Sherman Leung; Kevin W Graepel; Xiulian Du; Yongping Yang; Tongqing Zhou; Ulrich Baxa; Etsuko Yasuda; Tim Beaumont; Azad Kumar; Kayvon Modjarrad; Zizheng Zheng; Min Zhao; Ningshao Xia; Peter D Kwong; Barney S Graham
Journal:  Science       Date:  2013-04-25       Impact factor: 47.728

10.  Antigenic presentation of heterologous epitopes engineered into the outer surface-exposed helix 4 loop region of human papillomavirus L1 capsomeres.

Authors:  Yoshihiko Murata; Paula M Lightfoote; Robert C Rose; Edward E Walsh
Journal:  Virol J       Date:  2009-06-18       Impact factor: 4.099
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