| Literature DB >> 9658142 |
W Kim1, Y Tang, Y Okada, T A Torrey, S K Chattopadhyay, M Pfleiderer, F G Falkner, F Dorner, W Choi, N Hirokawa, H C Morse.
Abstract
A cDNA clone encoding a cellular protein that interacts with murine leukemia virus (MuLV) Gag proteins was isolated from a T-cell lymphoma library. The sequence of the clone is identical to the C terminus of a cellular protein, KIF4, a microtubule-associated motor protein that belongs to the kinesin superfamily. KIF4-MuLV Gag associations have been detected in vitro and in vivo in mammalian cells. We suggest that KIF4 could be involved in Gag polyprotein translocation from the cytoplasm to the cell membrane.Entities:
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Year: 1998 PMID: 9658142 PMCID: PMC109902
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103