| Literature DB >> 9658138 |
Abstract
Transcription of the vaccinia virus genome is mediated by a virus-encoded multisubunit DNA-dependent RNA polymerase in conjunction with early-, intermediate-, and late-stage-specific factors. Previous studies indicated that two virus-encoded proteins (capping enzyme and VITF-1) and one unidentified cellular protein (VITF-2) are required for specific transcription of an intermediate promoter template in vitro. We have now extensively purified an additional virus-induced intermediate transcription factor with a native mass of approximately 100 kDa.Entities:
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Year: 1998 PMID: 9658138 PMCID: PMC109898
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103