Literature DB >> 9657056

Trypanocidal effects of curcumin in vitro.

M Nose1, T Koide, Y Ogihara, Y Yabu, N Ohta.   

Abstract

During the course of study searching for the antiparasitic agents from natural compounds, we found that curcumin showed cytotoxicity against African trypanosomes in vitro. The LD50 values of curcumin were 4.77 +/- 0.91 microM for bloodstream forms and 46.52 +/- 4.94 microM for procyclic forms of Trypanosoma brucei brucei (GUTat 3.1 clone).

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Year:  1998        PMID： 9657056     DOI： 10.1248/bpb.21.643

Source DB:  PubMed          Journal:  Biol Pharm Bull        ISSN： 0918-6158            Impact factor:   2.233


  16 in total

1.  Curcumin-loaded into PLGA nanoparticles: preparation and in vitro schistosomicidal activity.

Authors:  Priscilla P Luz; Lizandra G Magalhães; Ana Carolina Pereira; Wilson R Cunha; Vanderlei Rodrigues; Marcio L Andrade E Silva
Journal:  Parasitol Res       Date:  2011-07-08       Impact factor: 2.289

2.  Effects of curcumin (diferuloylmethane) on Eimeria tenella sporozoites in vitro.

Authors:  Reda E Khalafalla; Uwe Müller; Md Shahiduzzaman; Viktor Dyachenko; Abdelrazik Y Desouky; Gottfried Alber; Arwid Daugschies
Journal:  Parasitol Res       Date:  2010-10-30       Impact factor: 2.289

3.  Validity of silver, chitosan, and curcumin nanoparticles as anti-Giardia agents.

Authors:  D E Said; L M Elsamad; Y M Gohar
Journal:  Parasitol Res       Date:  2012-03-06       Impact factor: 2.289

Review 4.  Discovery of curcumin, a component of golden spice, and its miraculous biological activities.

Authors:  Subash C Gupta; Sridevi Patchva; Wonil Koh; Bharat B Aggarwal
Journal:  Clin Exp Pharmacol Physiol       Date:  2012-03       Impact factor: 2.557

5.  Cytotoxic effect of curcumin on malaria parasite Plasmodium falciparum: inhibition of histone acetylation and generation of reactive oxygen species.

Authors:  Long Cui; Jun Miao; Liwang Cui
Journal:  Antimicrob Agents Chemother       Date:  2006-12-04       Impact factor: 5.191

6.  Curcumin overcomes the inhibitory effect of nitric oxide on Leishmania.

Authors:  Marion Man-Ying Chan; Naga Suresh Adapala; Dunne Fong
Journal:  Parasitol Res       Date:  2005-03-17       Impact factor: 2.289

7.  In vitro schistosomicidal activity of curcumin against Schistosoma mansoni adult worms.

Authors:  Lizandra G Magalhães; Carla Botelho Machado; Enyara Rezende Morais; Erika Bueno de Carvalho Moreira; Cláudia Sossai Soares; Sérgio Henrique da Silva; Ademar A Da Silva Filho; Vanderlei Rodrigues
Journal:  Parasitol Res       Date:  2008-12-19       Impact factor: 2.289

8.  Effects of curcumin on Cryptosporidium parvum in vitro.

Authors:  M Shahiduzzaman; V Dyachenko; R E Khalafalla; A Y Desouky; A Daugschies
Journal:  Parasitol Res       Date:  2009-06-26       Impact factor: 2.289

Review 9.  Lysine acetylation: elucidating the components of an emerging global signaling pathway in trypanosomes.

Authors:  Victoria Lucia Alonso; Esteban Carlos Serra
Journal:  J Biomed Biotechnol       Date:  2012-10-03

10.  In vitro study of parasite elimination and endothelial protection by curcumin: adjunctive therapy for cerebral malaria.

Authors:  Sarun Kunwittaya; Lertyot Treeratanapiboon; Apapan Srisarin; Chartchalerm Isarankura-Na-Ayudhya; Virapong Prachayasittikul
Journal:  EXCLI J       Date:  2014-03-20       Impact factor: 4.068
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