Literature DB >> 9656083

[Vector electrocardiographic findings in chronic Chagas cardiomyopathy].

P C Montenegro Valdovinos1, A de Micheli, P A Reyes López.   

Abstract

Dilated Cardiomyopathy (DCM) is associated with many diseases. By means of epidemiologic, clinical and invasive diagnostic techniques, the etiology of DCM is identified almost in 50% of the cases. Chronic infection with Trypanosoma cruzi is recognized as a cause of DCM in Latin America. A blind study of 40 cases of DCM explores the electrovectorcardiographic data obtained in chronic chagasic cardiomyopathy (CCC). Twenty one of 40 patients fulfilled epidemiologic and seroimmunologic criteria for CCC, 19 had DCM. There were not differences between these groups in regard to sex or age. Patients suffering DCM had in addition diabetes mellitus, systemic hypertension or ischemic heart disease. Those with CCC had not comorbid diseases in 50% of the cases. Arrhythmias and conduction blocks were equally recognized in both groups, as well as ECG evidence of injury or necrosis (p > 0.05). However, ECG signs of subepicardial ischemia were a dominant feature in patients with CCC and normal epicardial coronary arteries (p < 0.05). Probably this finding is due to a small vessels damage, a pathogenic mechanism proposed in CCC.

Entities:  

Mesh:

Year:  1998        PMID: 9656083

Source DB:  PubMed          Journal:  Arch Inst Cardiol Mex


  1 in total

1.  Plasmid DNA immunization with Trypanosoma cruzi genes induces cardiac and clinical protection against Chagas disease in the canine model.

Authors:  Olivia Rodríguez-Morales; M Magdalena Pérez-Leyva; Martha A Ballinas-Verdugo; Silvia C Carrillo-Sánchez; J Luis Rosales-Encina; Ricardo Alejandre-Aguilar; Pedro A Reyes; Minerva Arce-Fonseca
Journal:  Vet Res       Date:  2012-11-13       Impact factor: 3.683

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.