Literature DB >> 9655938

Molecular cloning and characterisation of a mouse gene encoding an isoform of the neuronal cyclin-dependent kinase 5 (CDK5) activator.

F Nildén1, A Bäckström, C Bark.   

Abstract

We have isolated and characterised the mouse gene for the p39 activator, designated p39is, which encodes a protein of 369 amino acids. The mouse p39 protein exhibits 95% amino acid identity to a previously characterised human p39 cDNA and the novel gene sequence corresponds to a single genomic locus in mouse. The p39is mRNA is highly expressed in the mouse central nervous system.

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Year:  1998        PMID： 9655938     DOI： 10.1016/s0167-4781(98)00073-6

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  4 in total

1.  Synergistic contributions of cyclin-dependant kinase 5/p35 and Reelin/Dab1 to the positioning of cortical neurons in the developing mouse brain.

Authors:  T Ohshima; M Ogawa; M Hirasawa; G Longenecker; K Ishiguro; H C Pant; R O Brady; A B Kulkarni; K Mikoshiba
Journal:  Proc Natl Acad Sci U S A       Date:  2001-02-13       Impact factor: 11.205

2.  p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment.

Authors:  J Ko; S Humbert; R T Bronson; S Takahashi; A B Kulkarni; E Li; L H Tsai
Journal:  J Neurosci       Date:  2001-09-01       Impact factor: 6.167

3.  Sp1 and Sp3 regulate transcription of the cyclin-dependent kinase 5 regulatory subunit 2 (p39) promoter in neuronal cells.

Authors:  Alvaro Valin; Julie D Cook; Sarah Ross; Christi L Saklad; Grace Gill
Journal:  Biochim Biophys Acta       Date:  2009-03

4.  Neuronal expression of muskelin in the rodent central nervous system.

Authors:  Nadia Tagnaouti; Sven Loebrich; Frank Heisler; Yvonne Pechmann; Susanne Fehr; Adèle De Arcangelis; Elisabeth Georges-Labouesse; Josephine C Adams; Matthias Kneussel
Journal:  BMC Neurosci       Date:  2007-05-02       Impact factor: 3.288
  4 in total

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