| Literature DB >> 9654777 |
C Dunstan1, B Liu, C J Welch, P Perera, L Bohlin.
Abstract
The new phenolic compound, 3,5-dihydroxy-4-methoxy phenethyl alcohol, named alphitol, and betulinic acid were from the bark of Alphitonia zizyphoides. The chemical structure of alphitol was determined by mass spectrometry in combination with one and two dimensional NMR, including HMBC. Both compounds inhibited prostaglandin biosynthesis in vitro, alphitol with an IC50 value of 0.66mM, which is of the same magnitude as acetyl salicylic acid.Entities:
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Year: 1998 PMID： 9654777 DOI： 10.1016/s0031-9422(97)00827-3
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072