Literature DB >> 96531

Choice behavior in rhesus monkeys: cocaine versus food.

T G Aigner, R L Balster.   

Abstract

Rhesus monkeys were allowed to choose between intravenous injections of cocaine and food reinforcement for lever pressing. A choice trial was available every 15 minutes continuously for 8 days. The animals chose cocaine almost exclusively, which resulted in high cocaine intake, decreased food intake, weight loss, and marked behavioral toxicity. The study provides evidence of the reinforcing efficacy of cocaine.

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Year:  1978        PMID： 96531     DOI： 10.1126/science.96531

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  39 in total

1.  Exploring the limits and utility of operant conditioning in the treatment of drug addiction.

Authors:  Kenneth Silverman
Journal:  Behav Anal       Date:  2004

2.  Preference for cocaine- versus pup-associated cues differentially activates neurons expressing either Fos or cocaine- and amphetamine-regulated transcript in lactating, maternal rodents.

Authors:  B J Mattson; J I Morrell
Journal:  Neuroscience       Date:  2005       Impact factor: 3.590

3.  Long-term cocaine self-administration under fixed-ratio and second-order schedules in monkeys.

Authors:  Paul W Czoty; Beth A Reboussin; Tonya L Calhoun; Susan H Nader; Michael A Nader
Journal:  Psychopharmacology (Berl)       Date:  2007-01-10       Impact factor: 4.530

4.  Essential value of cocaine and food in rats: tests of the exponential model of demand.

Authors:  Chesley J Christensen; Alan Silberberg; Steven R Hursh; Mary E Huntsberry; Anthony L Riley
Journal:  Psychopharmacology (Berl)       Date:  2008-03-20       Impact factor: 4.530

5.  Effects of increasing the magnitude of an alternative reinforcer on drug choice in a discrete-trials choice procedure.

Authors:  M A Nader; W L Woolverton
Journal:  Psychopharmacology (Berl)       Date:  1991       Impact factor: 4.530

Review 6.  William L. Woolverton: a case history in unraveling the behavioral pharmacology of stimulants.

Authors:  Michael A Nader; Robert L Balster; Jack E Henningfield
Journal:  Neuropharmacology       Date:  2014-05-20       Impact factor: 5.250

Review 7.  Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications.

Authors:  Rita Z Goldstein; Nora D Volkow
Journal:  Nat Rev Neurosci       Date:  2011-10-20       Impact factor: 34.870

8.  Cocaine and food as reinforcers: effects of reinforcer magnitude and response requirement under second-order fixed-ratio and progressive-ratio schedules.

Authors:  D J Spear; J L Katz
Journal:  J Exp Anal Behav       Date:  1991-09       Impact factor: 2.468

Review 9.  Animal models of drug craving.

Authors:  A Markou; F Weiss; L H Gold; S B Caine; G Schulteis; G F Koob
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

10.  Effects of extended cocaine access and cocaine withdrawal on choice between cocaine and food in rhesus monkeys.

Authors:  Matthew L Banks; S Stevens Negus
Journal:  Neuropsychopharmacology       Date:  2010-01       Impact factor: 7.853
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