Literature DB >> 965200

Piromidic acid and its ethylic ester: absorption, distribution, excretion.

S Rosini, D Benetti.   

Abstract

The absorption, distribution and excretion of piromidic acid and its ethyl ester were investigated in the rat. When administered orally the ethyl ester was well absorbed and subsequently hydrolysed, giving much higher blood and tissue concentration than a corresponding dose of the parent compound. The antimicrobial activity of urine and bile samples was also investigated.

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Year:  1976        PMID: 965200     DOI: 10.1007/BF02081992

Source DB:  PubMed          Journal:  Int Urol Nephrol        ISSN: 0301-1623            Impact factor:   2.370


  2 in total

1.  Piromidic acid, a new antibacterial agent: antibacterial properties.

Authors:  M Shimizu; S Nakamura; Y Takase
Journal:  Antimicrob Agents Chemother (Bethesda)       Date:  1970

2.  Piromidic acid, a new antibacterial agent: absorption, distribution, excretion, and metabolism.

Authors:  M Shimizu; Y Sekine; H Higuchi; H Suzuki; S Nakamura
Journal:  Antimicrob Agents Chemother (Bethesda)       Date:  1970
  2 in total

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