Literature DB >> 9651623

Pathomechanisms and pathophysiology of isocyanate-induced diseases--summary of present knowledge.

M Raulf-Heimsoth1, X Baur.   

Abstract

During recent years in Western countries, diisocyanates are one of the main causes of occupational asthma. The mechanism of diisocyanate-induced asthma is still unknown but recent evidence suggests immunological mechanisms, including cell-mediated immune responses. Immune responses to isocyanates may result in different illnesses, cell- and/or antibody-mediated entities. In addition, irritative, toxic, and mutagenic effects may occur. This review summarizes current knowledge of the pathomechanisms, including immunological and nonimmunological (mutagenic and genotoxic) aspects of isocyanate disorders.

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Year:  1998        PMID： 9651623     DOI： 10.1002/(sici)1097-0274(199808)34:2<137::aid-ajim6>3.0.co;2-u

Source DB:  PubMed          Journal:  Am J Ind Med        ISSN： 0271-3586            Impact factor:   2.214


  11 in total

1.  Influence of polymorphic metabolic enzymes on biotransformation and effects of diphenylmethane diisocyanate.

Authors:  Margareta Littorin; Saimei Hou; Karin Broberg; Jonas Björk; Susanne Fält; Galbani Abdoulaye; Malgorzata Kalemba; Charlotta Ryk; Staffan Skerfving
Journal:  Int Arch Occup Environ Health       Date:  2007-08-04       Impact factor: 3.015

2.  Increase in exhaled nitric oxide (eNO) after work-related isocyanate exposure.

Authors:  L Barbinova; X Baur
Journal:  Int Arch Occup Environ Health       Date:  2006-01-19       Impact factor: 3.015

3.  Respiratory symptoms, sensitization, and exposure response relationships in spray painters exposed to isocyanates.

Authors:  Anjoeka Pronk; Liesbeth Preller; Monika Raulf-Heimsoth; Irene C L Jonkers; Jan-Willem Lammers; Inge M Wouters; Gert Doekes; Adam V Wisnewski; Dick Heederik
Journal:  Am J Respir Crit Care Med       Date:  2007-07-26       Impact factor: 21.405

4.  Host factors in occupational diisocyanate asthma: a Swiss longitudinal study.

Authors:  M Berode; M Jost; M Ruegger; H Savolainen
Journal:  Int Arch Occup Environ Health       Date:  2005-02-16       Impact factor: 3.015

5.  Inception cohort study of workers exposed to toluene diisocyanate at a polyurethane foam factory: initial one-year follow-up.

Authors:  Wei Gui; Adam V Wisnewski; Iulia Neamtiu; Eugen Gurzau; Judith A Sparer; Meredith H Stowe; Jian Liu; Martin D Slade; Olivia A Rusu; Carrie A Redlich
Journal:  Am J Ind Med       Date:  2014-09-29       Impact factor: 2.214

6.  Exposure biomarkers and risk from gluing and heating of polyurethane: a cross sectional study of respiratory symptoms.

Authors:  M Littorin; L Rylander; G Skarping; M Dalene; H Welinder; U Strömberg; S Skerfving
Journal:  Occup Environ Med       Date:  2000-06       Impact factor: 4.402

7.  Review of the occupational exposure to isocyanates: Mechanisms of action.

Authors:  Kazuko Nakashima; Tatsuya Takeshita; Kanehisa Morimoto
Journal:  Environ Health Prev Med       Date:  2002-04       Impact factor: 3.674

8.  Biomonitoring Human Albumin Adducts: The Past, the Present, and the Future.

Authors:  Gabriele Sabbioni; Robert J Turesky
Journal:  Chem Res Toxicol       Date:  2016-12-18       Impact factor: 3.739

9.  Occupational airborne exposure, specific sensitization and the atopic status: evidence of a complex interrelationship.

Authors:  Xaver Baur; Liubov Barbinova
Journal:  J Occup Med Toxicol       Date:  2013-02-13       Impact factor: 2.646

Review 10.  Herbal bioactivation: the good, the bad and the ugly.

Authors:  Shufeng Zhou; Hwee-Ling Koh; Yihuai Gao; Zhi-yuan Gong; Edmund Jon Deoon Lee
Journal:  Life Sci       Date:  2004-01-09       Impact factor: 5.037
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