Literature DB >> 9651148

1-[2(R)-(2-amino-2-methylpropionylamino)-3-(1H-indol-3-yl)propionyl]- 3-benzylpiperidine-3(S)-carboxylic acid ethyl ester (L-163,540): a potent, orally bioavailable, and short-duration growth hormone secretagogue.

L Yang1, G Morriello, A A Patchett, K Leung, T Jacks, K Cheng, K D Schleim, W Feeney, W W Chan, S H Chiu, R G Smith.   

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Year:  1998        PMID: 9651148     DOI: 10.1021/jm9800191

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  2 in total

1.  Small molecule mimetics of an HIV-1 gp41 fusion intermediate as vaccine leads.

Authors:  Michael J Caulfield; Vadim Y Dudkin; Elizabeth A Ottinger; Krista L Getty; Paul D Zuck; Robin M Kaufhold; Robert W Hepler; Georgia B McGaughey; Michael Citron; Renee C Hrin; Ying-Jie Wang; Michael D Miller; Joseph G Joyce
Journal:  J Biol Chem       Date:  2010-10-13       Impact factor: 5.157

2.  In vitro and in vivo trans-esterification of 1-[2(R)-(2-amino-2-methylpropionylamino)-3-(1H-indol-3-yl)propionyl]-3(S)-benzyl-piperidine-3-carboxylic acid ethyl ester and the effects of ethanol on its pharmacokinetics in rats.

Authors:  Zhesheng Chen; Arun K Agrawal; Ronald B Franklin; Kwan H Leung; Shuet-Hing Lee Chiu
Journal:  Pharm Res       Date:  2004-06       Impact factor: 4.200

  2 in total

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