Literature DB >> 965099

H and M antigens of Histoplasma capsulatum: preparation of antisera and location of these antigens in yeast-phase cells.

J H Green, W K Harrell, S B Gray, J E Johnson, R C Bolin, H Gross, G B Malcolm.   

Abstract

Antiserum has been prepared in rabbits against the H and M antigens of H. capsulatum with immunoelectrophoretic precipitin arcs used as vaccines. The antiserum is specific for H. capsulatum in the immunodiffusion test and can be used as reference serum for identifying antibodies to these antigens in sera from suspected cases histoplasmosis. We found that (1) hand m antigens are not located on the surface of yeast-phase cells and (ii) complement fixation releases the antigens reactive in the complement fixation test from yeast-phase cells.

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Year:  1976        PMID: 965099      PMCID: PMC420959          DOI: 10.1128/iai.14.3.826-831.1976

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  17 in total

1.  THE PRODUCTION OF SPECIFIC RABBIT ANTIBODIES BY INJECTING INDIVIDUAL ANTIGEN-ANTIBODY COMPLEXES SEPARATED FROM MIXED ANTIGENS.

Authors:  H SMITH; R C GALLOP; B T TOZER
Journal:  Immunology       Date:  1964-03       Impact factor: 7.397

2.  Evaluation of the agar-plate precipitin test for histoplasmosis.

Authors:  J H SCHUBERT; H J LYNCH; L AJELLO
Journal:  Am Rev Respir Dis       Date:  1961-12

3.  Diagnosis of histoplasmosis using precipitin reactions in agargel.

Authors:  D C HEINER
Journal:  Pediatrics       Date:  1958-10       Impact factor: 7.124

4.  Serologic aspects of experimental histoplasmosis in cattle.

Authors:  R J Sharbaugh; A F DiSalvo; N L Goodman; R A Reddick
Journal:  J Infect Dis       Date:  1973-02       Impact factor: 5.226

Review 5.  Serology of systemic fungus diseases.

Authors:  L Aufman
Journal:  Public Health Rep       Date:  1966-02       Impact factor: 2.792

6.  Comparison of immunodiffusion and complement fixation tests in the diagnosis of histoplasmosis.

Authors:  D S Bauman; C D Smith
Journal:  J Clin Microbiol       Date:  1976-08       Impact factor: 5.948

7.  Evaluation of histoplasmin for the presence of H and M antigens: some difficulties encountered in the production and evaluation of a product suitable for the immunodiffusion test.

Authors:  H Gross; G Bradley; L Pine; S Gray; J H Green; W K Harrell
Journal:  J Clin Microbiol       Date:  1975-03       Impact factor: 5.948

8.  Preparation of a fluorescent antibody specific for the yeast phase of Histoplasma capsulatum.

Authors:  L KAUFMAN; W KAPLAN
Journal:  J Bacteriol       Date:  1961-11       Impact factor: 3.490

9.  Purification, composition, and serological characterization of histoplasmin-H and M antigens.

Authors:  G Bradley; L Pine; M W Reeves; C W Moss
Journal:  Infect Immun       Date:  1974-05       Impact factor: 3.441

10.  Pathogenesis and immunological aspects of experimental histoplasmosis in cynomolgus monkeys (Macaca fascicularis).

Authors:  W Kaplan; L Kaufman; H M McClure
Journal:  Infect Immun       Date:  1972-06       Impact factor: 3.441

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  13 in total

1.  Procedures for the production and separation of H and M antigens in histoplasmin: chemical and serological properties of the isolated products.

Authors:  L Pine; H Gross; G B Malcolm; J R George; S B Gray; C W Moss
Journal:  Mycopathologia       Date:  1977-10-28       Impact factor: 2.574

2.  Purified histoplasmin reagents for the identification of h and m antigens and homologous antibodies by immunodiffusion or complement fixation tests.

Authors:  L Pine; J H Green; H Gross; G B Malcolm; W K Harrell
Journal:  Mycopathologia       Date:  1985-07       Impact factor: 2.574

Review 3.  Exoantigen tests for the immunoidentification of fungal cultures.

Authors:  L Kaufman; P Standard; A A Padhye
Journal:  Mycopathologia       Date:  1983-04-22       Impact factor: 2.574

4.  Improved version of the exoantigen test for identification of Coccidioides immitis and Histoplasma capsulatum cultures.

Authors:  L Kaufman; P Standard
Journal:  J Clin Microbiol       Date:  1978-07       Impact factor: 5.948

5.  Preparation of reference antisera for laboratory diagnosis of blastomycosis.

Authors:  J H Green; W K Harrell; J E Johnson; R Benson
Journal:  J Clin Microbiol       Date:  1979-07       Impact factor: 5.948

6.  Detection of two Blastomyces dermatitidis serotypes by exoantigen analysis.

Authors:  L Kaufman; P G Standard; R J Weeks; A A Padhye
Journal:  J Clin Microbiol       Date:  1983-07       Impact factor: 5.948

7.  Immuno-identification of cultures of fungi pathogenic to man.

Authors:  L Kaufman; P Standard
Journal:  Curr Microbiol       Date:  1978       Impact factor: 2.188

8.  Solid-phase competitive-binding radioimmunoassay for detecting antibody to the M antigen of histoplasmin.

Authors:  E Reiss; H Hutchinson; L Pine; D W Ziegler; L Kaufman
Journal:  J Clin Microbiol       Date:  1977-12       Impact factor: 5.948

9.  Affinity purification and characterization of Shiga-like toxin II and production of toxin-specific monoclonal antibodies.

Authors:  F P Downes; T J Barrett; J H Green; C H Aloisio; J S Spika; N A Strockbine; I K Wachsmuth
Journal:  Infect Immun       Date:  1988-08       Impact factor: 3.441

10.  In situ localization of antigens of Histoplasma capsulatum using colloidal gold immune electron microscopy.

Authors:  J R Graybill; M Patiño; J Ahrens
Journal:  Mycopathologia       Date:  1988-12       Impact factor: 2.574

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