Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Isolation of a purified skin test antigen from Blastomyces dermatitidis yeast-phase cell wall.

Literature DB >> 965086

Isolation of a purified skin test antigen from Blastomyces dermatitidis yeast-phase cell wall.

Abstract

Preparative polyacrylamide gel electrophoresis was used to isolate individual components of an alkaline-soluble-water-soluble fraction of the cell wall of Blastomyces dermatitidis yeast phase. One component isolated demonstrated exceptional specificity and reactivity when tested on guinea pigs infected with B. dermatitidis. This component displayed no cross-reactivity when tested on animals infected with Histoplasma capsulatum. The significance of isolation of a purified, specific antigen is discussed.

Entities: Chemical Species

Mesh：

Substances：
Antigens, Fungal

Year: 1976 PMID： 965086 PMCID： PMC420931 DOI： 10.1128/iai.14.3.623-625.1976

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

7 in total

1. DISC ELECTROPHORESIS. II. METHOD AND APPLICATION TO HUMAN SERUM PROTEINS.

Authors: B J DAVIS
Journal: Ann N Y Acad Sci Date: 1964-12-28 Impact factor: 5.691

2. Delayed hypersensitivity in experimental fungus infections: the skin reactivity of antigens from the yeast phase of Blastomyces dermatitidis.

Authors: J E DYSON; E E EVANS
Journal: J Invest Dermatol Date: 1955-04 Impact factor: 8.551

3. Polysaccharide skin test antigens derived from Histoplasma capsulatum and Blastomyces dermatitidis.

Authors: R A KNIGHT; S MARCUS
Journal: Am Rev Tuberc Date: 1958-06

4. Preparative isotachophoretic separation of skin test antigens from blastomycin purified derivative.

Authors: M V Lancaster; R F Sprouse
Journal: Infect Immun Date: 1976-03 Impact factor: 3.441

5. Histoplasmin potency as affected by culture age.

Authors: N L Goodman; R F Spouse; H W Larsh
Journal: Sabouraudia Date: 1968-10

6. Yeast- and mycelial-phase antigens of Blastomyces dermatitidis: comparison using disc gel electrophoresis.

Authors: R A Cox; H W Larsh
Journal: Infect Immun Date: 1974-07 Impact factor: 3.441

7. Isolation of skin test-active preparations from yeast-phase cells of Blastomyces dermatitidis.

Authors: R A Cox; H W Larsh
Journal: Infect Immun Date: 1974-07 Impact factor: 3.441

7 in total

8 in total

5. Isolation, purification, and radiolabeling of a novel 120-kD surface protein on Blastomyces dermatitidis yeasts to detect antibody in infected patients.

Authors: B S Klein; J M Jones
Journal: J Clin Invest Date: 1990-01 Impact factor: 14.808

6. WI-1, a novel 120-kilodalton surface protein on Blastomyces dermatitidis yeast cells, is a target antigen of cell-mediated immunity in human blastomycosis.

Authors: B S Klein; P M Sondel; J M Jones
Journal: Infect Immun Date: 1992-10 Impact factor: 3.441

7. Detection of antibody responses and delayed dermal hypersensitivity with Blastomyces dermatitidis yeast and mycelial lysate antigens.

Authors: B W Seawell; J Y Wheeler; K Yearsley; K L Alexander; A M Legendre; G M Scalarone
Journal: Mycopathologia Date: 1991-06 Impact factor: 2.574

8. Use of an alkali-soluble water-soluble extract of Blastomyces dermatitidis yeast-phase cell walls and isoelectrically focused components in peripheral lymphocyte transformations.

Authors: N K Hall; F Deighton; H W Larsh
Journal: Infect Immun Date: 1978-02 Impact factor: 3.441