Literature DB >> 9650055

A Taenia solium oncosphere protein homologous to host-protective Taenia ovis and Taenia saginata 18 kDa antigens.

C G Gauci1, A Flisser, M W Lightowlers.   

Abstract

A Taenia solium cDNA (TSOL-18) encoding a protein with close homology to host protective oncosphere antigens from Taenia ovis (To18) and Taenia saginata (TSA-18) is described here. TSOL-18 was cloned from mRNA obtained from hatched and activated oncospheres of T. solium. The high level of predicted amino acid sequence homology among TSOL-18 and other host protective taeniid antigens suggests that the protein expressed by TSOL-18 may be capable of being used as a vaccine against T. solium infection in the parasite's intermediate hosts.

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Year:  1998        PMID： 9650055     DOI： 10.1016/s0020-7519(98)00034-4

Source DB:  PubMed          Journal:  Int J Parasitol        ISSN： 0020-7519            Impact factor:   3.981


  17 in total

1.  The Taenia saginata homologue of the major surface antigen of Echinococcus spp. is immunogenic and 97% identical to its Taenia solium homologue.

Authors:  Luis Miguel González; Elizabeth Ferrer; Andrea Spickett; Lynne M Michael; Adriano F Vatta; Teresa Gárate; Leslie J S Harrison; R Michael E Parkhouse
Journal:  Parasitol Res       Date:  2007-08-03       Impact factor: 2.289

2.  Molecular characterization of the Taenia solium Tso31 antigen and homologous of other Taenia species from Peru.

Authors:  Ana Vargas-Calla; Luis A Gomez-Puerta; Maria T Lopez; Hector H Garcia; Armando E Gonzalez
Journal:  Parasitol Res       Date:  2019-01-09       Impact factor: 2.289

3.  Molecular and functional characterization of a Taenia adhesion gene family (TAF) encoding potential protective antigens of Taenia saginata oncospheres.

Authors:  Luis Miguel Gonzalez; Pedro Bonay; Laura Benitez; Elizabeth Ferrer; Leslie J S Harrison; R Michael E Parkhouse; Teresa Garate
Journal:  Parasitol Res       Date:  2006-10-18       Impact factor: 2.289

4.  Genes encoding homologous antigens in taeniid cestode parasites: Implications for development of recombinant vaccines produced in Escherichia coli.

Authors:  Charles Gauci; Marshall W Lightowlers
Journal:  Bioengineered       Date:  2012-05-01       Impact factor: 3.269

5.  Expression of Multiple Taenia Solium Immunogens in Plant Cells Through a Ribosomal Skip Mechanism.

Authors:  Elizabeth Monreal-Escalante; Bernardo Bañuelos-Hernández; Marisela Hernández; Gladis Fragoso; Teresa Garate; Edda Sciutto; Sergio Rosales-Mendoza
Journal:  Mol Biotechnol       Date:  2015-07       Impact factor: 2.695

6.  Induction of protection against porcine cysticercosis by vaccination with recombinant oncosphere antigens.

Authors:  Ana Flisser; Charles G Gauci; André Zoli; Joel Martinez-Ocaña; Adriana Garza-Rodriguez; Jose Luis Dominguez-Alpizar; Pablo Maravilla; Rossana Rodriguez-Canul; Guillermina Avila; Laura Aguilar-Vega; Craig Kyngdon; Stanny Geerts; Marshall W Lightowlers
Journal:  Infect Immun       Date:  2004-09       Impact factor: 3.441

7.  Towards the development of an oral vaccine against porcine cysticercosis: expression of the protective HP6/TSOL18 antigen in transgenic carrots cells.

Authors:  Elizabeth Monreal-Escalante; Dania O Govea-Alonso; Marisela Hernández; Jacquelynne Cervantes; Jorge A Salazar-González; Andrea Romero-Maldonado; Gabriela Rosas; Teresa Garate; Gladis Fragoso; Edda Sciutto; Sergio Rosales-Mendoza
Journal:  Planta       Date:  2015-11-27       Impact factor: 4.116

Review 8.  Taenia solium cysticercosis.

Authors:  Héctor H García; Armando E Gonzalez; Carlton A W Evans; Robert H Gilman
Journal:  Lancet       Date:  2003-08-16       Impact factor: 79.321

9.  Effective production and purification of the glycosylated TSOL18 antigen, which is protective against pig cysticercosis.

Authors:  Xuepeng Cai; Gailing Yuan; Yadong Zheng; Xuenong Luo; Shaohua Zhang; Juntao Ding; Zhizhong Jing; Chengping Lu
Journal:  Infect Immun       Date:  2007-12-10       Impact factor: 3.441

10.  Vaccination with recombinant oncosphere antigens reduces the susceptibility of sheep to infection with Taenia multiceps.

Authors:  Charles Gauci; Gulay Vural; Taraneh Oncel; Antonio Varcasia; Veronica Damian; Craig T Kyngdon; Philip S Craig; Garry A Anderson; Marshall W Lightowlers
Journal:  Int J Parasitol       Date:  2007-11-24       Impact factor: 3.981
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