RATIONALE AND OBJECTIVES: The goal of this study was to evaluate and differentiate breast lesions in patients by sonographic measurements performed using CARI sonography. METHODS: Thirty-one patients with 33 histologically proven breast lesions were examined by mammography, conventional ultrasound sonography, and CARI sonography. Investigation with mammography-like positioning was performed in case of CARI sonography. The ratios of the lesion diameters were calculated in a craniocaudal and a mediolateral plane. The results were compared with the results obtained with conventional modalities. RESULTS: Breast lesions were detected with the best sensitivity (100%) and a high specificity (86%) using B-mode ultrasound sonography. Mammography resulted in a sensitivity of 92% and a specificity of 91%, whereas the CARI sonography yielded 100% sensitivity and 67% specificity. CONCLUSIONS: The differentiation of lesions by measurements performed with CARI sonography resulted in a high sensitivity. The specificity, however, was inferior compared with the other imaging modalities. This may limit the routine application of the technique for clinical diagnoses of breast lesions. However, due to the small number of patients investigated in this pilot study, the full potential should be evaluated in a larger collective of patients.
RATIONALE AND OBJECTIVES: The goal of this study was to evaluate and differentiate breast lesions in patients by sonographic measurements performed using CARI sonography. METHODS: Thirty-one patients with 33 histologically proven breast lesions were examined by mammography, conventional ultrasound sonography, and CARI sonography. Investigation with mammography-like positioning was performed in case of CARI sonography. The ratios of the lesion diameters were calculated in a craniocaudal and a mediolateral plane. The results were compared with the results obtained with conventional modalities. RESULTS:Breast lesions were detected with the best sensitivity (100%) and a high specificity (86%) using B-mode ultrasound sonography. Mammography resulted in a sensitivity of 92% and a specificity of 91%, whereas the CARI sonography yielded 100% sensitivity and 67% specificity. CONCLUSIONS: The differentiation of lesions by measurements performed with CARI sonography resulted in a high sensitivity. The specificity, however, was inferior compared with the other imaging modalities. This may limit the routine application of the technique for clinical diagnoses of breast lesions. However, due to the small number of patients investigated in this pilot study, the full potential should be evaluated in a larger collective of patients.
Authors: Rebecca C Booi; Jochen F Krücker; Mitchell M Goodsitt; Matthew O'Donnell; Ajay Kapur; Gerald L LeCarpentier; Marilyn A Roubidoux; J Brian Fowlkes; Paul L Carson Journal: Ultrasound Med Biol Date: 2007-03 Impact factor: 2.998
Authors: Rüdiger Schulz-Wendtland; Sebastian M Jud; Peter A Fasching; Arndt Hartmann; Marcus Radicke; Claudia Rauh; Michael Uder; Marius Wunderle; Paul Gass; Hanna Langemann; Matthias W Beckmann; Julius Emons Journal: Geburtshilfe Frauenheilkd Date: 2017-04-27 Impact factor: 2.915
Authors: Eric D Larson; Won-Mean Lee; Marilyn A Roubidoux; Mitchel M Goodsitt; Chris Lashbrook; Fouzaan Zafar; Oliver D Kripfgans; Kai Thomenius; Paul L Carson Journal: Ultrasound Med Biol Date: 2016-06-03 Impact factor: 2.998