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Literature DB >> 96471

A twin study on three enzymes (DBH, COMT, MAO) of catecholamine metabolism. Correlations with MMPI.

H Winter, M Herschel, P Propping, W Friedl, F Vogel.

Abstract

Ina a sample of 48 healthy adult male twin pairs (24 MZ, 24 DZ) the activities of DBH (serum), COMT (red blood cells), and MAO (platelets) were determined. The twins had undergone a detailed psychodiagnostic test procedure before. Interindividual variability of enzyme activities is almost exclusively genetically determined. No correlation between enzyme activities within one subject is found. Correlations between enzyme activities and MMPI test scores were calculated. As in a comparable investigation by Murphy et al. (1977), negative correlations between MAO activity and MMPI scores prevailed.

Entities: Chemical Gene

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Year: 1978 PMID： 96471 DOI： 10.1007/bf00426959

Source DB: PubMed Journal: Psychopharmacology (Berl) ISSN： 0033-3158 Impact factor: 4.530

32 in total

1. Reduced monoamine oxidase activity in blood platelets from schizophrenic patients.

Authors: D L Murphy; R J Wyatt
Journal: Nature Date: 1972-07-28 Impact factor: 49.962

2. Correlation of erythrocyte catechol-O-methyltransferase activity between siblings.

Authors: R M Weinshilboum; F A Raymond; L R Elveback; W H Weidman
Journal: Nature Date: 1974-12-06 Impact factor: 49.962

3. Genetic control of plasma dopamine-beta-hydroxylase.

Authors: S B Ross; L Wetterberg; M Myrhed
Journal: Life Sci Date: 1973-06-15 Impact factor: 5.037

4. Reduced monoamine oxidase activity in blood platelets from bipolar depressed patients.

Authors: D L Murphy; R Weiss
Journal: Am J Psychiatry Date: 1972-05 Impact factor: 18.112

5. Microassay of human erythrocyte catechol-O-methyltransferase: removal of inhibitory calcium ion with chelating resin.

Authors: F A Raymond; R M Weinshilboum
Journal: Clin Chim Acta Date: 1975-01-20 Impact factor: 3.786

6. A genetic study of plasma dopamine beta hydroxylase activity in man.

Authors: J Mendlewicz; M Levitt; J L Fleiss
Journal: Acta Genet Med Gemellol (Roma) Date: 1975

7. The biochemical high-risk paradigm: behavioral and familial correlates of low platelet monoamine oxidase activity.

Authors: M S Buchsbaum; R D Coursey; D L Murphy
Journal: Science Date: 1976-10-15 Impact factor: 47.728

8. The effects of testosterone on plasma and platelet monoamine oxidase (MAO) an plasma dopamine-beta-hydroxylase (DBH) activities in the male rhesus monkey.

Authors: D E Redmond; J Baulu; D L Murphy; D L Loriaux; M G Zeigler; C R Lake
Journal: Psychosom Med Date: 1976 Sep-Oct Impact factor: 4.312

Review 9. NIH conference. Dopamine- -hydroxylase. Basic and clinical studies.

Authors: I J Kopin; S Kaufman; H Viveros; D Jacobowitz; C R Lake; M G Ziegler; W Lovenberg; F K Goodwin
Journal: Ann Intern Med Date: 1976-08 Impact factor: 25.391

10. The oestrous cycle and monoamine oxidase activity.

Authors: M Holzbauer; M B Youdim
Journal: Br J Pharmacol Date: 1973-08 Impact factor: 8.739

9 in total

1. The electroencephalogram (EEG) as a research tool in human behavior genetics: psychological examinations in healthy males with various inherited EEG variants. I. Rationale of the study. Material. Methods. Heritability of test parameters.

Authors: F Vogel; E Schalt; J Krüger; P Propping; K F Lehnert
Journal: Hum Genet Date: 1979-02-28 Impact factor: 4.132

2. Platelet monoamine oxidase (MAO) activity: evidence for a single major locus.

Authors: J Rice; P McGuffin; L R Goldin; E G Shaskan; E S Gershon
Journal: Am J Hum Genet Date: 1984-01 Impact factor: 11.025

3. The electroencephalogram (EEG) as a research tool in human behavior genetics: psychological examinations in healthy males with various inherited EEG variants. III. Interpretation of the results.

Authors: F Vogel; E Schalt
Journal: Hum Genet Date: 1979-02-28 Impact factor: 4.132

4. Platelet monoamine oxidase in healthy subjects: the "biochemical high-risk paradigm" revisited.

Authors: P Propping; E R Rey; W Friedl; H Beckmann
Journal: Arch Psychiatr Nervenkr (1970) Date: 1981

5. Platelet monoamine oxidase activity in first-degree relatives of schizophrenic patients.

Authors: P Propping; W Friedl
Journal: Psychopharmacology (Berl) Date: 1979-11 Impact factor: 4.530

6. Segregation and linkage studies of plasma dopamine-beta-hydroxylase (DBH), erythrocyte catechol-O-methyltransferase (COMT), and platelet monoamine oxidase (MAO): possible linkage between the ABO locus and a gene controlling DBH activity.

Authors: L R Goldin; E S Gershon; C R Lake; D L Murphy; M McGinniss; R S Sparkes
Journal: Am J Hum Genet Date: 1982-03 Impact factor: 11.025