Literature DB >> 9646177

TGF-beta: a balancing act.

N L McCartney-Francis1, M Frazier-Jessen, S M Wahl.   

Abstract

Regulation of developmental processes as well as host defense and repair mechanisms requires the maintenance of a delicate balance of positive and negative regulatory signals. TGF-beta, a molecule known for its many diverse activities, can promote or inhibit cell growth and function. Disruption of the balance between these opposing activities can contribute to aberrant development, malignancy, or pathogenic immune and inflammatory responses. TGF-beta transgenic mouse studies highlight the essential function(s) of TGF-beta and its receptors and provide insight to potential therapeutic approaches to manipulate TGF-beta expression.

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Year:  1998        PMID： 9646177     DOI： 10.3109/08830189809043009

Source DB:  PubMed          Journal:  Int Rev Immunol        ISSN： 0883-0185            Impact factor:   5.311


  13 in total

Review 1.  Cytokine-based immunointervention in the treatment of autoimmune diseases.

Authors:  L Adorini
Journal:  Clin Exp Immunol       Date:  2003-05       Impact factor: 4.330

Review 2.  Uric acid as a mediator of diabetic nephropathy.

Authors:  Diana I Jalal; David M Maahs; Peter Hovind; Takahiko Nakagawa
Journal:  Semin Nephrol       Date:  2011-09       Impact factor: 5.299

3.  FAK is required for TGFbeta-induced JNK phosphorylation in fibroblasts: implications for acquisition of a matrix-remodeling phenotype.

Authors:  Shangxi Liu; Shi-wen Xu; Laura Kennedy; Daphne Pala; Yunliang Chen; Mark Eastwood; David E Carter; Carol M Black; David J Abraham; Andrew Leask
Journal:  Mol Biol Cell       Date:  2007-04-04       Impact factor: 4.138

4.  Transforming growth factor beta/Smad3 signaling regulates IRF-7 function and transcriptional activation of the beta interferon promoter.

Authors:  Jing Qing; Cheng Liu; Lisa Choy; Rui-Yun Wu; Joseph S Pagano; Rik Derynck
Journal:  Mol Cell Biol       Date:  2004-02       Impact factor: 4.272

Review 5.  Scar wars: is TGFbeta the phantom menace in scleroderma?

Authors:  Andrew Leask
Journal:  Arthritis Res Ther       Date:  2006       Impact factor: 5.156

Review 6.  Mechanotransduction Mechanisms in Mitral Valve Physiology and Disease Pathogenesis.

Authors:  Leah A Pagnozzi; Jonathan T Butcher
Journal:  Front Cardiovasc Med       Date:  2017-12-22

7.  Quantification of active and total transforming growth factor-β levels in serum and solid organ tissues by bioassay.

Authors:  Shaukat A Khan; Jennifer Joyce; Takeshi Tsuda
Journal:  BMC Res Notes       Date:  2012-11-14

8.  Engagement of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) induces transforming growth factor beta (TGF-beta) production by murine CD4(+) T cells.

Authors:  W Chen; W Jin; S M Wahl
Journal:  J Exp Med       Date:  1998-11-16       Impact factor: 14.307

9.  Expression of TGFbeta family in the developing internal ear of rat embryos.

Authors:  Ho-Jeong Kim; Ki-Young Kang; Jin-Ghi Baek; Hyoung-Chul Jo; Hyun Kim
Journal:  J Korean Med Sci       Date:  2006-02       Impact factor: 2.153

10.  Effective treatment for prevention of post-operative adhesion after strabismus surgery in experimental rabbit model: 0.5 % tranilast ophthalmic solution.

Authors:  Sang Uk Choi; Kyoung Woo Kim; Nam Ju Moon
Journal:  BMC Ophthalmol       Date:  2016-09-21       Impact factor: 2.209
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