| Literature DB >> 9645916 |
M A Khanin1, D V Rakov, A E Kogan.
Abstract
A mathematical model for the prothrombin time test is proposed. The time course of clotting factor activation during coagulation was calculated, and the sensitivity of the test to a decrease in the concentrations of coagulation proteins or their activities was studied. The model predicts that only severe coagulation disorders connected with a more than five-fold decrease in the concentrations or activities of the blood coagulation factors can be revealed by the test.Entities:
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Year: 1998 PMID： 9645916 DOI： 10.1016/s0049-3848(97)00288-0
Source DB: PubMed Journal: Thromb Res ISSN： 0049-3848 Impact factor: 3.944