Literature DB >> 9645728

Rifabutin-associated uveitis in an immunosuppressed pediatric patient without acquired immunodeficiency syndrome.

D A Jewelewicz1, W M Schiff, S Brown, G R Barile.   

Abstract

PURPOSE: To describe a case of bilateral, symptomatic rifabutin-associated uveitis with hypopyon and vitreal opacities in an immunosuppressed pediatric patient without acquired immunodeficiency syndrome (AIDS).
METHOD: Case report. An 8-year-old boy presented with bilateral uveitis 24 months after a bilateral lung transplant.
RESULTS: Our patient, whose medications included rifabutin, clarithromycin, and immunosuppressive agents, responded to discontinuation of the rifabutin and initiation of intensive topical corticosteroid therapy with complete resolution of the uveitis.
CONCLUSION: Rifabutin-associated uveitis may occur in a non-AIDS pediatric patient.

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Year:  1998        PMID: 9645728     DOI: 10.1016/s0002-9394(98)00056-7

Source DB:  PubMed          Journal:  Am J Ophthalmol        ISSN: 0002-9394            Impact factor:   5.258


  2 in total

1.  Rifabutin-associated hypopyon uveitis and retinal vasculitis with a history of acute myeloid leukemia.

Authors:  Wendy M Smith; Madhu G Reddy; Kelly A Hutcheson; Rachel J Bishop; H Nida Sen
Journal:  J Ophthalmic Inflamm Infect       Date:  2012-02-04

2.  Rifabutin pharmacokinetics and safety among TB/HIV-coinfected children receiving lopinavir/ritonavir-containing second-line ART.

Authors:  Holly E Rawizza; Regina Oladokun; Emeka Ejeliogu; Stephen Oguche; Babatunde O Ogunbosi; Oche Agbaji; Georgina Odaibo; Godwin Imade; David Olaleye; Lubbe Wiesner; Kristin M Darin; Prosper Okonkwo; Phyllis J Kanki; Kimberly K Scarsi; Helen M McIlleron
Journal:  J Antimicrob Chemother       Date:  2021-02-11       Impact factor: 5.790

  2 in total

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