Literature DB >> 9645212

[Primary radiotherapy of recurrent Merkel cell carcinoma of the eyelid. Case report and review of the literature].

S Höcht1, T Wiegel.   

Abstract

BACKGROUND: Despite an increasing number of reports Merkel-cell-carcinoma still is a rare neoplasm. Reports on radical radiotherapy are sparse. PATIENT AND
METHOD: We report on a successful radical radiotherapy of a recurrent Merkel-cell-carcinoma of the eyelid in an 84-year old woman, using a hypofractionated treatment of 50 Gy with 70 kV-X-rays, 10 fractions of 5 Gy within 5 weeks. RESULT: Rapid and complete remission was achieved, with no signs of local or distant failure 24 months after the end of therapy.
CONCLUSION: The case reported on highlights the radiosensitivity of this tumor and the role of radiotherapy not merely as salvage procedure.

Entities:  

Mesh:

Year:  1998        PMID: 9645212     DOI: 10.1007/bf03038545

Source DB:  PubMed          Journal:  Strahlenther Onkol        ISSN: 0179-7158            Impact factor:   3.621


  34 in total

1.  Merkel cell tumour of the face successfully treated with radical radiotherapy.

Authors:  I K Pople
Journal:  Eur J Surg Oncol       Date:  1988-02       Impact factor: 4.424

Review 2.  Radiation therapy for skin tumors.

Authors:  S J Westgate
Journal:  Otolaryngol Clin North Am       Date:  1993-04       Impact factor: 3.346

3.  Primary neuroendocrine carcinoma of the eyelid, immunohistochemical and ultrastructural study.

Authors:  R Proença; M F Santos; J G Cunha-Vaz
Journal:  Int Ophthalmol       Date:  1990-07       Impact factor: 2.031

4.  Merkel cell carcinoma. Prognosis and management.

Authors:  A Yiengpruksawan; D G Coit; H T Thaler; C Urmacher; W K Knapper
Journal:  Arch Surg       Date:  1991-12

5.  Radiotherapy for Merkel cell carcinoma of the skin of the head and neck.

Authors:  M Suntharalingam; M S Rudoltz; W M Mendenhall; J T Parsons; S P Stringer; R R Million
Journal:  Head Neck       Date:  1995 Mar-Apr       Impact factor: 3.147

Review 6.  Neuroendocrine (Merkel cell) carcinoma of the skin. Its natural history, diagnosis, and treatment.

Authors:  C L Hitchcock; K I Bland; R G Laney; D Franzini; B Harris; E M Copeland
Journal:  Ann Surg       Date:  1988-02       Impact factor: 12.969

7.  Chemotherapy for Merkel cell carcinoma with carboplatin and etoposide.

Authors:  D Pectasides; G Moutzourides; M Dimitriadis; J Varthalitis; A Athanassiou
Journal:  Am J Clin Oncol       Date:  1995-10       Impact factor: 2.339

8.  Merkel cell carcinoma of the eyelid.

Authors:  J B Soltau; M E Smith; P L Custer
Journal:  Am J Ophthalmol       Date:  1996-03       Impact factor: 5.258

9.  Further insights into the natural history and management of primary cutaneous neuroendocrine (Merkel cell) carcinoma.

Authors:  F Boyle; S Pendlebury; D Bell
Journal:  Int J Radiat Oncol Biol Phys       Date:  1995-01-15       Impact factor: 7.038

10.  Chromosomes 1, 11, and 13 are frequently involved in karyotypic abnormalities in metastatic Merkel cell carcinoma.

Authors:  J H Leonard; P Leonard; J H Kearsley
Journal:  Cancer Genet Cytogenet       Date:  1993-05
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