| Literature DB >> 9644301 |
M Tanaka1, R Kimura, A Matsutani, K Zaitsu, Y Oka, K Oizumi.
Abstract
A case report of simultaneous presentation of chronic myelogenous leukemia (CML) and multiple myeloma (MM) in a 72-year-old female is described. Our case was typical of Ph1-positive and chimeric bcr-abl messenger RNA-positive CML. Furthermore, a marked IgG (kappa-type) paraproteinemia was present. Fluorescence in situ hybridization showed that 97% of marrow nucleated cells were positive for bcr-abl fusion signal, when myeloma cells in the bone marrow amounted to 19.0%. In the literature survey, 4 similar cases with coexistence of CML and MM have been identified.Entities:
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Year: 1998 PMID: 9644301 DOI: 10.1159/000040843
Source DB: PubMed Journal: Acta Haematol ISSN: 0001-5792 Impact factor: 2.195