Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Two (Z)-dehydrobutyrine-containing microcystins from a hepatotoxic bloom of Oscillatoria agardhii from Soulseat Loch, Scotland.

Literature DB >> 9644085

Two (Z)-dehydrobutyrine-containing microcystins from a hepatotoxic bloom of Oscillatoria agardhii from Soulseat Loch, Scotland.

Abstract

Two (Z)-dehydrobutyrine(Dhb)-containing microcystins, [d-Asp3, (Z)-Dhb7]microcystin-HtyR (1) and [d-Asp3, (Z)-Dhb7]microcystin-LR (2), were isolated from a hepatotoxic bloom of the cyanobacterium Oscillatoria agardhii from a freshwater lake in Scotland. The geometrical structure of the Dhb units in the microcystins was determined as Z on the basis of NOE and ROESY experiments.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1998 PMID： 9644085 DOI： 10.1021/np980047m

Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050

Keyword Cloud
Cited

8 in total

1. Detailed study of cyanobacterial microcystins using high performance tandem mass spectrometry.

Authors: Yulin Qi; Stella Bortoli; Dietrich A Volmer
Journal: J Am Soc Mass Spectrom Date: 2014-04-30 Impact factor: 3.109

2. Structures of pahayokolides A and B, cyclic peptides from a Lyngbya sp.

Authors: Tianying An; Thallapuranam Krishnaswamy Suresh Kumar; Minglei Wang; Li Liu; Jackson O Lay; Rohana Liyanage; John Berry; Miroslav Gantar; Vered Marks; Robert E Gawley; Kathleen S Rein
Journal: J Nat Prod Date: 2007-04-14 Impact factor: 4.050

3. Hassallidins, antifungal glycolipopeptides, are widespread among cyanobacteria and are the end-product of a nonribosomal pathway.

Authors: Johanna Vestola; Tania K Shishido; Jouni Jokela; David P Fewer; Olli Aitio; Perttu Permi; Matti Wahlsten; Hao Wang; Leo Rouhiainen; Kaarina Sivonen
Journal: Proc Natl Acad Sci U S A Date: 2014-04-17 Impact factor: 11.205

8. High levels of structural diversity observed in microcystins from Microcystis CAWBG11 and characterization of six new microcystin congeners.

Authors: Jonathan Puddick; Michèle R Prinsep; Susanna A Wood; Sangata A F Kaufononga; Stephen Craig Cary; David P Hamilton
Journal: Mar Drugs Date: 2014-11-13 Impact factor: 5.118

8 in total

Two (Z)-dehydrobutyrine-containing microcystins from a hepatotoxic bloom of Oscillatoria agardhii from Soulseat Loch, Scotland.

1. Detailed study of cyanobacterial microcystins using high performance tandem mass spectrometry.

2. Structures of pahayokolides A and B, cyclic peptides from a Lyngbya sp.

3. Hassallidins, antifungal glycolipopeptides, are widespread among cyanobacteria and are the end-product of a nonribosomal pathway.

4. Further characterization of glycine-containing microcystins from the McMurdo dry Valleys of Antarctica.

5. Selectivity and potency of microcystin congeners against OATP1B1 and OATP1B3 expressing cancer cells.

6. Effects of the amino acid constituents of microcystin variants on cytotoxicity to primary cultured rat hepatocytes.

Review 7. α,β-Dehydroamino acids in naturally occurring peptides.

8. High levels of structural diversity observed in microcystins from Microcystis CAWBG11 and characterization of six new microcystin congeners.