Literature DB >> 9642560

[Lichen planopilaris simulating postmenopausal frontal fibrosing alopecia (Kossard)].

R M Trüeb1, R Torricelli.   

Abstract

A 68-year old woman presented with a frontal fibrosing alopecia and lesions of the buccal mucous membranes typical for lichen planus. Postmenopausal frontal fibrosing alopecia (PFFA) has recently been described by Kossard as a distinct entity characterized by progressive recession of the frontotemporal and parietal hair margins leading to permanent alopecia in the form of a symmetrical band-like area of scanning in postmenopausal women. The histology (perifollicular lymphocytic infiltration and fibrosis, increase of apoptosis of hair follicle keratinocytes) is indistinguishable from that of lichen planopilaris. The localization and age- and sex-related characteristics of PFFA are not sufficient to delineate it as a discrete entity from lichen planopilaris. Our observation of oral lichen planus in a postmenopausal woman with frontal fibrosing alopecia points to the possibility that PFFA actually may represent a variant of lichen planopilaris with a predilection for the frontotemporal hairline. Other variants of lichen planopilaris include multifocal lichen planopilaris, disseminated lichen planopilaris (Lassueur-Graham-Little syndrome), lichenoid pseudopelade, and any combination of these ("mixed type"). An effective therapy of PFFA is not known. Also, treatment of lichen planopilaris forms in which fibrosis predominates over inflammation is similarly problematic, but the natural course of these diseases seems to be self-limited.

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Mesh:

Year:  1998        PMID: 9642560     DOI: 10.1007/s001050050760

Source DB:  PubMed          Journal:  Hautarzt        ISSN: 0017-8470            Impact factor:   0.751


  10 in total

1.  Cutaneous Lupus Erythematosus Presenting as Frontal Fibrosing Alopecia: Report of 2 Patients.

Authors:  Ralph M Trüeb; Laila El Shabrawi-Caelen; Werner Kempf
Journal:  Skin Appendage Disord       Date:  2017-05-31

Review 2.  [Frontal fibrosing alopecia].

Authors:  G Wagner; V Meyer; M M Sachse
Journal:  Hautarzt       Date:  2016-11       Impact factor: 0.751

3.  [Frontal fibrosing alopecia with androgenetic pattern. A diagnostic challenge - a therapeutic problem].

Authors:  L Trémezaygues; T Vogt; C S L Müller
Journal:  Hautarzt       Date:  2012-05       Impact factor: 0.751

4.  [Cicatricial alopecias].

Authors:  R M Trüeb
Journal:  Hautarzt       Date:  2013-11       Impact factor: 0.751

Review 5.  Frontal Fibrosing Alopecia: A Review.

Authors:  María Librada Porriño-Bustamante; María Antonia Fernández-Pugnaire; Salvador Arias-Santiago
Journal:  J Clin Med       Date:  2021-04-21       Impact factor: 4.241

6.  Nail Involvement in Frontal Fibrosing Alopecia.

Authors:  Melanie Macpherson; Parinaz Hohendorf-Ansari; Ralph Michel Trüeb
Journal:  Int J Trichology       Date:  2015 Apr-Jun

7.  Facial Papules in Fibrosing Alopecia in a Pattern Distribution (Cicatricial Pattern Hair Loss).

Authors:  Ausrine Ramanauskaite; Ralph M Trüeb
Journal:  Int J Trichology       Date:  2015 Jul-Sep

8.  Familial Cicatricial Alopecia: Report of Familial Frontal Fibrosing Alopecia and Fibrosing Alopecia in a Pattern Distribution.

Authors:  Dandara Meurer Missio; Maria Fernanda Reis Gavazzoni Dias; Ralph Michel Trüeb
Journal:  Int J Trichology       Date:  2017 Jul-Sep

9.  Graham-Little-Piccardi Syndrome: A Lens Through beyond What is Known.

Authors:  Abhijit Saha; Joly Seth; Anupam Das; Sandipan Dhar
Journal:  Int J Trichology       Date:  2016 Oct-Dec

10.  Lichen Planopilaris Caused by Wig Attachment: A Case of Koebner Phenomenon in Frontal Fibrosing Alopecia.

Authors:  Priscila Taguti; Hudson Dutra; Ralph Michel Trüeb
Journal:  Int J Trichology       Date:  2018 Jul-Aug
  10 in total

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