Literature DB >> 9639187

Clarithromycin induced digoxin toxicity.

S P Nordt1, S R Williams, A S Manoguerra, R F Clark.   

Abstract

A case of digoxin poisoning following the co-administration of digoxin and clarithromycin in a 28 year old male is described. Since the aetiology of chronic digoxin poisoning is often unclear, clinicians should be aware of the potential drug-drug interaction between digoxin and clarithromycin.

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Year:  1998        PMID: 9639187      PMCID: PMC1343067          DOI: 10.1136/emj.15.3.194

Source DB:  PubMed          Journal:  J Accid Emerg Med        ISSN: 1351-0622


  8 in total

Review 1.  Digitalis. Mechanisms of action and clinical use.

Authors:  T W Smith
Journal:  N Engl J Med       Date:  1988-02-11       Impact factor: 91.245

2.  Hyperkalemia in acute digitalis poisoning: prognostic significance and therapeutic implications.

Authors:  C Bismuth; M Gaultier; F Conso; M L Efthymiou
Journal:  Clin Toxicol       Date:  1973       Impact factor: 4.467

3.  Clarithromycin-related toxic effects of digoxin.

Authors:  S R Midoneck; O R Etingin
Journal:  N Engl J Med       Date:  1995-11-30       Impact factor: 91.245

4.  Pitfalls in the administration of digoxin-specific Fab fragments.

Authors:  R F Clark; E D Barton
Journal:  J Emerg Med       Date:  1994 Mar-Apr       Impact factor: 1.484

5.  Inactivation of digoxin by the gut flora: reversal by antibiotic therapy.

Authors:  J Lindenbaum; D G Rund; V P Butler; D Tse-Eng; J R Saha
Journal:  N Engl J Med       Date:  1981-10-01       Impact factor: 91.245

Review 6.  Cardiac glycosides. Drug interactions of clinical significance.

Authors:  B Magnani; P L Malini
Journal:  Drug Saf       Date:  1995-02       Impact factor: 5.606

7.  Digoxin toxicity due to interaction of digoxin with erythromycin.

Authors:  D L Maxwell; S K Gilmour-White; M R Hall
Journal:  BMJ       Date:  1989-03-04

8.  Digoxin-inactivating bacteria: identification in human gut flora.

Authors:  J R Saha; V P Butler; H C Neu; J Lindenbaum
Journal:  Science       Date:  1983-04-15       Impact factor: 47.728

  8 in total
  1 in total

Review 1.  Pharmacokinetic aspects of treating infections in the intensive care unit: focus on drug interactions.

Authors:  F Pea; M Furlanut
Journal:  Clin Pharmacokinet       Date:  2001       Impact factor: 5.577

  1 in total

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