AIMS: This is a hitherto unreported case of an epithelioid haemangioendothelioma of the thyroid gland. METHODS AND RESULTS: The patient was a 44-year-old woman who presented with a right thyroid mass. A right subtotal thyroidectomy was performed. Histologically the lesion had characteristic epithelioid and spindle cell proliferation in a background of chondromyxoid stroma. Cytoplasmic vacuolization in the epithelioid and spindle cells was present. No atypical mitotic activity or necrosis was noted. The tumour cells were positive for factor VIII-related antigen, Ulex europeus and CD 31 and were negative for cytokeratin. CONCLUSION: The patient has been followed for 24 months and is free of recurrent and metastatic disease, which is supportive of a benign course in the thyroid gland.
AIMS: This is a hitherto unreported case of an epithelioid haemangioendothelioma of the thyroid gland. METHODS AND RESULTS: The patient was a 44-year-old woman who presented with a right thyroid mass. A right subtotal thyroidectomy was performed. Histologically the lesion had characteristic epithelioid and spindle cell proliferation in a background of chondromyxoid stroma. Cytoplasmic vacuolization in the epithelioid and spindle cells was present. No atypical mitotic activity or necrosis was noted. The tumour cells were positive for factor VIII-related antigen, Ulex europeus and CD 31 and were negative for cytokeratin. CONCLUSION: The patient has been followed for 24 months and is free of recurrent and metastatic disease, which is supportive of a benign course in the thyroid gland.
Authors: Jabeen Naqvi; Nelson G Ordonez; Mario A Luna; Michelle D Williams; Randal S Weber; Adel K El-Naggar Journal: Head Neck Pathol Date: 2007-10-26
Authors: Akeesha A Shah; N Paul Ohori; Linwah Yip; Christopher Coyne; Cristina R Antonescu; Raja R Seethala Journal: Endocr Pathol Date: 2016-06 Impact factor: 3.943