Literature DB >> 9638078

Effect of single and divided dose administration on the pharmacokinetics of albendazole in sheep and goat.

P K Sanyal1.   

Abstract

The pharmacokinetics of albendazole were studied in sheep and goats following single and divided dose administration at nematocidal and flukicidal dose rates. The disposition curves of the metabolites indicated increased uptake of the drug both in sheep and goats at divided dose schedules compared to single dose administration (P < 0.05). The increased bioavailability of benzimidazole anthelmintics in divided dose schedules could improve their efficacy and help in extending their lives.

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Year:  1998        PMID： 9638078     DOI： 10.1016/s1090-0233(05)80028-0

Source DB:  PubMed          Journal:  Vet J        ISSN： 1090-0233            Impact factor:   2.688


  3 in total

1.  Influence of diet type and pretreatment fasting on the disposition kinetics of albendazole in sheep.

Authors:  D Singh; P K Sanyal; C P Swarnkar; F A Khan; P S Bhagwan
Journal:  Vet Res Commun       Date:  1999-06       Impact factor: 2.459

2.  The pharmacokinetics and efficacy of long-term low-level and split-dose administration of albendazole through in-feed formulations against ovine and caprine parasitic gastroenteritis.

Authors:  P K Sanyal
Journal:  Vet Res Commun       Date:  1998-11       Impact factor: 2.459

3.  Improvement of Albendazole Bioavailability with Menbutone Administration in Sheep.

Authors:  Raquel Diez; M Jose Diez; Juan J Garcia; Jose M Rodríguez; Cristina Lopez; Nelida Fernandez; Matilde Sierra; Ana M Sahagun
Journal:  Animals (Basel)       Date:  2022-02-14       Impact factor: 2.752
  3 in total

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