Literature DB >> 9637913

Anti-apoptosis therapy: a way of treating neural degeneration?

M D Jacobson1.   

Abstract

Many degenerative diseases involve apoptotic cell death--can they be treated with apoptosis inhibitors, while protecting the normal physiological function of the rescued cells? Reason for optimism comes from a recent study of mutant flies with an analogue of the human degenerative disease retinitis pigmentosa.

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Year:  1998        PMID： 9637913     DOI： 10.1016/s0960-9822(98)70267-2

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  4 in total

1.  Tendinopathy and tears of the rotator cuff are associated with hypoxia and apoptosis.

Authors:  R T Benson; S M McDonnell; H J Knowles; J L Rees; A J Carr; P A Hulley
Journal:  J Bone Joint Surg Br       Date:  2010-03

2.  blue cheese mutations define a novel, conserved gene involved in progressive neural degeneration.

Authors:  Kim D Finley; Philip T Edeen; Robert C Cumming; Michelle D Mardahl-Dumesnil; Barbara J Taylor; Maria H Rodriguez; Calvin E Hwang; Michael Benedetti; Michael McKeown
Journal:  J Neurosci       Date:  2003-02-15       Impact factor: 6.167

3.  Baculovirus apoptotic suppressor P49 is a substrate inhibitor of initiator caspases resistant to P35 in vivo.

Authors:  Stephen J Zoog; Jennifer J Schiller; Justin A Wetter; Nor Chejanovsky; Paul D Friesen
Journal:  EMBO J       Date:  2002-10-01       Impact factor: 11.598

4.  Pharmacophore modeling and docking studies on some nonpeptide-based caspase-3 inhibitors.

Authors:  Simant Sharma; Arijit Basu; R K Agrawal
Journal:  Biomed Res Int       Date:  2013-09-08       Impact factor: 3.411
  4 in total

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