Literature DB >> 9636794

[Treatment of post-traumatic acute anemia by recombinant human erythropoietin in Jehovah's Witnesses].

C Streef1, C Charpentier, G Audibert, M C Laxenaire.   

Abstract

A 20-year-old Jehovah's witness patient experienced a femur fracture, with a section of the femoral artery and vein. On admission, haemoglobin concentration was 5.6 g.dL-1 and haematocrit 17%. Because of aponevrotomy, blood losses persisted. As the patient refused blood transfusion, recombinant human erythropoietin and parenteral iron were administered, associated with mild hypothermia, sedation and mechanical ventilation. After 21 days, the haemoglobin concentration increased to 10.9 g.dL-1 and haematocrit to 33% Recombinant human erythropoietin and parenteral iron may provide an alternative safe and effective therapy in life-threatening anaemia when blood transfusions are not accepted by the patient.

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Year:  1996        PMID: 9636794     DOI: 10.1016/s0750-7658(97)85879-0

Source DB:  PubMed          Journal:  Ann Fr Anesth Reanim        ISSN: 0750-7658


  2 in total

1.  Clinical strategies for supporting the untransfusable hemorrhaging patient.

Authors:  Gavin M Melmed; Meredith E Hulsey; Mike Newhouse; Houston E Holmes; Edward J Mays
Journal:  Proc (Bayl Univ Med Cent)       Date:  2009-10

2.  Potential Efficacy of Erythropoietin on Reducing the Risk of Mortality in Patients with Traumatic Brain Injury: A Systematic Review and Meta-Analysis.

Authors:  Chengli Liu; Changsheng Huang; Jie Xie; Hui Li; Michael Hong; Xuemei Chen; Junmin Wang; Jiarui Wang; Zhanfei Li; Jian Wang; Wei Wang
Journal:  Biomed Res Int       Date:  2020-10-29       Impact factor: 3.411

  2 in total

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