Literature DB >> 9634890

Cellular origin of mucins of the ocular surface tear film.

I K Gipson1, T Inatomi.   

Abstract

In summary, we have demonstrated that the ocular surface epithelia express at least three mucin genes. We suggest that the gel-forming mucin MUC5AC is a major mucin forming the mucus gel of the tear film. We further suggest that MUC1 facilitates the spread of the MUC5-containing mucus on the ocular surface and, along with the mucus gel, prevents cell and debris adhesion to the ocular surface. The function of MUC4 at the ocular surface remains to be elucidated.

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Year:  1998        PMID: 9634890     DOI: 10.1007/978-1-4615-5359-5_32

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  18 in total

1.  EEDA: a protein associated with an early stage of stratified epithelial differentiation.

Authors:  Lijie Sun; David G Ryan; Mingyuan Zhou; Tung-Tien Sun; Robert M Lavker
Journal:  J Cell Physiol       Date:  2006-01       Impact factor: 6.384

2.  Diversity of mucins in labial glands of infants.

Authors:  Mechthild Stoeckelhuber; Marco R Kesting; Denys J Loeffelbein; Christoph Schmitz; Klaus-Dietrich Wolff
Journal:  Histol Histopathol       Date:  2020-03-12       Impact factor: 2.303

3.  Regional differences in rat conjunctival ion transport activities.

Authors:  Dongfang Yu; William R Thelin; Troy D Rogers; M Jackson Stutts; Scott H Randell; Barbara R Grubb; Richard C Boucher
Journal:  Am J Physiol Cell Physiol       Date:  2012-07-18       Impact factor: 4.249

Review 4.  Physicochemical properties of mucus and their impact on transmucosal drug delivery.

Authors:  Jasmim Leal; Hugh D C Smyth; Debadyuti Ghosh
Journal:  Int J Pharm       Date:  2017-09-14       Impact factor: 5.875

Review 5.  Biological functions of tear film.

Authors:  Stephen C Pflugfelder; Michael E Stern
Journal:  Exp Eye Res       Date:  2020-06-16       Impact factor: 3.467

6.  Loss of NHE8 expression impairs ocular surface function in mice.

Authors:  Hua Xu; Yang Zhao; Jing Li; Mingwu Wang; Fangru Lian; Minghong Gao; Fayez K Ghishan
Journal:  Am J Physiol Cell Physiol       Date:  2014-11-05       Impact factor: 4.249

7.  Glycan structures of ocular surface mucins in man, rabbit and dog display species differences.

Authors:  Louise Royle; Elizabeth Matthews; Anthony Corfield; Monica Berry; Pauline M Rudd; Raymond A Dwek; Stephen D Carrington
Journal:  Glycoconj J       Date:  2008-05-09       Impact factor: 2.916

8.  A novel fluorescent lipid probe for dry eye: retrieval by tear lipocalin in humans.

Authors:  Po-Ting Yeh; Richard Casey; Ben J Glasgow
Journal:  Invest Ophthalmol Vis Sci       Date:  2013-02-19       Impact factor: 4.799

Review 9.  Immune - Goblet cell interaction in the conjunctiva.

Authors:  Jehan Alam; Cintia S de Paiva; Stephen C Pflugfelder
Journal:  Ocul Surf       Date:  2020-01-14       Impact factor: 5.033

Review 10.  Gene Therapy in the Anterior Eye Segment.

Authors:  Cynthia Amador; Ruchi Shah; Sean Ghiam; Andrei A Kramerov; Alexander V Ljubimov
Journal:  Curr Gene Ther       Date:  2022       Impact factor: 4.391

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