Literature DB >> 9634693

Transcriptional cooperativity: bending over backwards and doing the flip.

T K Kerppola1.   

Abstract

The structures of the NFAT1-Fos-Jun-ARRE2 and MAT alpha 2-MCM1-STE6 transcription regulatory complexes reveal changes in protein conformation and DNA bending. Studies of the interaction between Fos-Jun and NFAT1 in solution corroborate the crystallographic analysis. These results manifest the flexibility required for cooperative binding to composite regulatory elements.

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Year:  1998        PMID： 9634693     DOI： 10.1016/s0969-2126(98)00057-4

Source DB:  PubMed          Journal:  Structure        ISSN： 0969-2126            Impact factor:   5.006


  5 in total

1.  Hepatocyte nuclear factor-6 stimulates transcription of the alpha-fetoprotein gene and synergizes with the retinoic-acid-receptor-related orphan receptor alpha-4.

Authors:  Habib Nacer-Cherif; Brigitte Bois-Joyeux; Guy G Rousseau; Frédéric P Lemaigre; Jean-Louis Danan
Journal:  Biochem J       Date:  2003-02-01       Impact factor: 3.857

2.  Identification of a minimal cis-element and cognate trans-factor(s) required for induction of Rac2 gene expression during K562 cell differentiation.

Authors:  Rajarajeswari Muthukrishnan; David G Skalnik
Journal:  Gene       Date:  2009-04-17       Impact factor: 3.688

3.  Inhibition of G-protein βγ signaling enhances T cell receptor-stimulated interleukin 2 transcription in CD4+ T helper cells.

Authors:  Evan A Yost; Thomas R Hynes; Cassandra M Hartle; Braden J Ott; Catherine H Berlot
Journal:  PLoS One       Date:  2015-01-28       Impact factor: 3.240

4.  Measuring spatial preferences at fine-scale resolution identifies known and novel cis-regulatory element candidates and functional motif-pair relationships.

Authors:  Ken Daigoro Yokoyama; Uwe Ohler; Gregory A Wray
Journal:  Nucleic Acids Res       Date:  2009-05-29       Impact factor: 16.971

5.  Position specific variation in the rate of evolution in transcription factor binding sites.

Authors:  Alan M Moses; Derek Y Chiang; Manolis Kellis; Eric S Lander; Michael B Eisen
Journal:  BMC Evol Biol       Date:  2003-08-28       Impact factor: 3.260
  5 in total

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