Literature DB >> 9634537

Pharmacogenetics of cancer therapy: getting personal.

E Y Krynetski1, W E Evans.   

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Year:  1998        PMID： 9634537      PMCID： PMC1377260          DOI： 10.1086/301941

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


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  36 in total

1.  Nm23-H1: genetic alterations and expression patterns in tumor metastasis.

Authors:  M T Hartsough; P S Steeg
Journal:  Am J Hum Genet       Date:  1998-07       Impact factor: 11.025

2.  Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes.

Authors:  L Iyer; C D King; P F Whitington; M D Green; S K Roy; T R Tephly; B L Coffman; M J Ratain
Journal:  J Clin Invest       Date:  1998-02-15       Impact factor: 14.808

3.  Familial deficiency of dihydropyrimidine dehydrogenase. Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity.

Authors:  R B Diasio; T L Beavers; J T Carpenter
Journal:  J Clin Invest       Date:  1988-01       Impact factor: 14.808

4.  Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance.

Authors:  C R Yates; E Y Krynetski; T Loennechen; M Y Fessing; H L Tai; C H Pui; M V Relling; W E Evans
Journal:  Ann Intern Med       Date:  1997-04-15       Impact factor: 25.391

5.  Pharmacogenetics of human thiopurine methyltransferase: kidney-erythrocyte correlation and immunotitration studies.

Authors:  L C Woodson; J H Dunnette; R M Weinshilboum
Journal:  J Pharmacol Exp Ther       Date:  1982-07       Impact factor: 4.030

6.  Thiopurine methyltransferase biochemical genetics: human lymphocyte activity.

Authors:  J A Van Loon; R M Weinshilboum
Journal:  Biochem Genet       Date:  1982-08       Impact factor: 1.890

7.  Identification of the polymorphically expressed CYP2C19 and the wild-type CYP2C9-ILE359 allele as low-Km catalysts of cyclophosphamide and ifosfamide activation.

Authors:  T K Chang; L Yu; J A Goldstein; D J Waxman
Journal:  Pharmacogenetics       Date:  1997-06

8.  Human erythrocyte thiopurine methyltransferase: radiochemical microassay and biochemical properties.

Authors:  R M Weinshilboum; F A Raymond; P A Pazmiño
Journal:  Clin Chim Acta       Date:  1978-05-02       Impact factor: 3.786

9.  Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity.

Authors:  R M Weinshilboum; S L Sladek
Journal:  Am J Hum Genet       Date:  1980-09       Impact factor: 11.025

10.  Oral 6-mercaptopurine in childhood leukemia: parent drug pharmacokinetics and active metabolite concentrations.

Authors:  L Lennard; D Keen; J S Lilleyman
Journal:  Clin Pharmacol Ther       Date:  1986-09       Impact factor: 6.875
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  18 in total

1.  Disequilibrium mapping of a quantitative-trait locus in an expanding population.

Authors:  M Slatkin
Journal:  Am J Hum Genet       Date:  1999-06       Impact factor: 11.025

Review 2.  Chemotherapy of childhood lymphoblastic leukaemia: the first 50 years.

Authors:  J Lilleyman
Journal:  Paediatr Drugs       Date:  1999 Jul-Sep       Impact factor: 3.022

3.  Clinical Pharmacogenetics Implementation Consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing.

Authors:  M V Relling; E E Gardner; W J Sandborn; K Schmiegelow; C-H Pui; S W Yee; C M Stein; M Carrillo; W E Evans; T E Klein
Journal:  Clin Pharmacol Ther       Date:  2011-01-26       Impact factor: 6.875

4.  Epistatic interactions between thiopurine methyltransferase (TPMT) and inosine triphosphate pyrophosphatase (ITPA) variations determine 6-mercaptopurine toxicity in Indian children with acute lymphoblastic leukemia.

Authors:  Patchva Dorababu; Narayana Nagesh; Vijay Gandhi Linga; Sadashivudu Gundeti; Vijay Kumar Kutala; Pallu Reddanna; Raghunadharao Digumarti
Journal:  Eur J Clin Pharmacol       Date:  2011-10-19       Impact factor: 2.953

5.  Development and implementation of a pharmacist-managed clinical pharmacogenetics service.

Authors:  Kristine R Crews; Shane J Cross; John N McCormick; Donald K Baker; Alejandro R Molinelli; Richard Mullins; Mary V Relling; James M Hoffman
Journal:  Am J Health Syst Pharm       Date:  2011-01-15       Impact factor: 2.637

Review 6.  Pharmacogenetics as a molecular basis for individualized drug therapy: the thiopurine S-methyltransferase paradigm.

Authors:  E Y Krynetski; W E Evans
Journal:  Pharm Res       Date:  1999-03       Impact factor: 4.200

7.  Clinical Pharmacogenetics Implementation Consortium Guideline for Thiopurine Dosing Based on TPMT and NUDT15 Genotypes: 2018 Update.

Authors:  Mary V Relling; Matthias Schwab; Michelle Whirl-Carrillo; Guilherme Suarez-Kurtz; Ching-Hon Pui; Charles M Stein; Ann M Moyer; William E Evans; Teri E Klein; Federico Guillermo Antillon-Klussmann; Kelly E Caudle; Motohiro Kato; Allen E J Yeoh; Kjeld Schmiegelow; Jun J Yang
Journal:  Clin Pharmacol Ther       Date:  2019-01-20       Impact factor: 6.875

8.  Pharmacogenomic studies of the anticancer and immunosuppressive thiopurines mercaptopurine and azathioprine.

Authors:  Ahmed F Hawwa; Jeff S Millership; Paul S Collier; Koen Vandenbroeck; Anthony McCarthy; Sid Dempsey; Carole Cairns; John Collins; Colin Rodgers; James C McElnay
Journal:  Br J Clin Pharmacol       Date:  2008-06-28       Impact factor: 4.335

9.  The human ITPA polymorphic variant P32T is destabilized by the unpacking of the hydrophobic core.

Authors:  Peter D Simone; Lucas R Struble; Admir Kellezi; Carrie A Brown; Corinn E Grabow; Irine Khutsishvili; Luis A Marky; Youri I Pavlov; Gloria E O Borgstahl
Journal:  J Struct Biol       Date:  2013-03-23       Impact factor: 2.867

10.  cDNA microarray analysis of vascular gene expression after nitric oxide donor infusions in rats: implications for nitrate tolerance mechanisms.

Authors:  Ellen Q Wang; Woo-In Lee; Daniel Brazeau; Ho-Leung Fung
Journal:  AAPS PharmSci       Date:  2002
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