The structure of schizophrenic symptoms: a meta-analytic confirmatory factor analysis.

To quantitatively review all presently available evidence about the interrelations between positive and negative schizophrenic symptoms, we created an aggregate matrix of the intercorrelations among schizophrenic symptoms by combining data from 28 independent samples using meta-analytic procedures (net bivariate dfs ranging from 683 to 1657). Using confirmatory factor analyses, we then statistically compared four theoretically derived models of the structure of schizophrenic symptoms. Although a three-factor model (Liddle, 1987) best fit the data, results suggest that either more factors or different symptoms are required to account well for the latent structure underlying schizophrenic symptomatology. The nature of such augmented approaches, the opportunities and constraints inherent to multifactorial models, and the limitations of current instruments are discussed.