Literature DB >> 9633746

CSF levels of carnitine in children with meningitis, neurologic disorders, acute gastroenteritis, and seizure.

M Shinawi1, N Gruener, A Lerner.   

Abstract

Carnitine concentrations in CSF, serum, and urine in normal febrile children and children with meningitis, neurologic disorders, and dehydration were studied. Carnitine levels in CSF were 1/10 compared with serum in normal febrile children. These levels increased two- to three-fold in the pathologic conditions studied. Since damage to the blood-brain barrier occurs in these conditions, higher blood-brain barrier permeability might explain CNS carnitine accumulation.

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Year:  1998        PMID： 9633746     DOI： 10.1212/wnl.50.6.1869

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  11 in total

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