Literature DB >> 9632629

Inhibition of class II major histocompatibility complex antigen processing by Escherichia coli heat-labile enterotoxin requires an enzymatically active A subunit.

M P Matousek1, J G Nedrud, W Cieplak, C V Harding.   

Abstract

Escherichia coli heat-labile enterotoxin (LT) and cholera toxin (CT) were found to inhibit intracellular antigen processing. Processing was not inhibited by mutant LT with attenuated ADP-ribosyltransferase activity, CT B or LT B subunit, which enhanced presentation of preexisting cell surface peptide-class II major histocompatibility complex complexes. Inhibition of antigen processing correlated with A subunit ADP-ribosyltransferase activity.

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Year:  1998        PMID： 9632629      PMCID： PMC108376          DOI： 10.1128/IAI.66.7.3480-3484.1998

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  34 in total

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Authors:  A Bromander; J Holmgren; N Lycke
Journal:  J Immunol       Date:  1991-05-01       Impact factor: 5.422

2.  Cholera toxin enhances alloantigen presentation by cultured intestinal epithelial cells.

Authors:  A K Bromander; M Kjerrulf; J Holmgren; N Lycke
Journal:  Scand J Immunol       Date:  1993-04       Impact factor: 3.487

3.  Cholera toxin adjuvant greatly promotes antigen priming of T cells.

Authors:  E Hörnquist; N Lycke
Journal:  Eur J Immunol       Date:  1993-09       Impact factor: 5.532

Review 4.  Proteolytic activation of bacterial toxins: role of bacterial and host cell proteases.

Authors:  V M Gordon; S H Leppla
Journal:  Infect Immun       Date:  1994-02       Impact factor: 3.441

5.  A new rapid and simple non-radioactive assay to monitor and determine the proliferation of lymphocytes: an alternative to [3H]thymidine incorporation assay.

Authors:  S A Ahmed; R M Gogal; J E Walsh
Journal:  J Immunol Methods       Date:  1994-04-15       Impact factor: 2.303

6.  Protection of germ-free mice from infection by Helicobacter felis after active oral or passive IgA immunization.

Authors:  S J Czinn; A Cai; J G Nedrud
Journal:  Vaccine       Date:  1993       Impact factor: 3.641

7.  Recombinant Escherichia coli express a defined, cytoplasmic epitope that is efficiently processed in macrophage phagolysosomes for class II MHC presentation to T lymphocytes.

Authors:  J D Pfeifer; M J Wick; D G Russell; S J Normark; C V Harding
Journal:  J Immunol       Date:  1992-10-15       Impact factor: 5.422

8.  The adjuvant effect of Vibrio cholerae and Escherichia coli heat-labile enterotoxins is linked to their ADP-ribosyltransferase activity.

Authors:  N Lycke; T Tsuji; J Holmgren
Journal:  Eur J Immunol       Date:  1992-09       Impact factor: 5.532

9.  Effect of site-directed mutagenic alterations on ADP-ribosyltransferase activity of the A subunit of Escherichia coli heat-labile enterotoxin.

Authors:  Y Lobet; C W Cluff; W Cieplak
Journal:  Infect Immun       Date:  1991-09       Impact factor: 3.441

10.  Killed Campylobacter elicits immune response and protection when administered with an oral adjuvant.

Authors:  F M Rollwagen; N D Pacheco; J D Clements; O Pavlovskis; D M Rollins; R I Walker
Journal:  Vaccine       Date:  1993-10       Impact factor: 3.641
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  5 in total

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Authors:  A George-Chandy; K Eriksson; M Lebens; I Nordström; E Schön; J Holmgren
Journal:  Infect Immun       Date:  2001-09       Impact factor: 3.441

2.  Peptide-receptive class I major histocompatibility complex molecules on TAP-deficient and wild-type cells and their roles in the processing of exogenous antigens.

Authors:  R Song; A Porgador; C V Harding
Journal:  Immunology       Date:  1999-06       Impact factor: 7.397

3.  Escherichia coli heat-labile enterotoxin B subunit is a more potent mucosal adjuvant than its vlosely related homologue, the B subunit of cholera toxin.

Authors:  D G Millar; T R Hirst; D P Snider
Journal:  Infect Immun       Date:  2001-05       Impact factor: 3.441

4.  Cholera toxin suppresses interleukin (IL)-12 production and IL-12 receptor beta1 and beta2 chain expression.

Authors:  M C Braun; J He; C Y Wu; B L Kelsall
Journal:  J Exp Med       Date:  1999-02-01       Impact factor: 14.307

5.  Bordetella adenylate cyclase toxin differentially modulates toll-like receptor-stimulated activation, migration and T cell stimulatory capacity of dendritic cells.

Authors:  Irena Adkins; Jana Kamanova; Aneta Kocourkova; Martina Svedova; Jakub Tomala; Hana Janova; Jiri Masin; Barbora Chladkova; Ladislav Bumba; Marek Kovar; Padraig J Ross; Ludmila Tuckova; Radek Spisek; Kingston H G Mills; Peter Sebo
Journal:  PLoS One       Date:  2014-08-01       Impact factor: 3.240
  5 in total

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