Literature DB >> 9632102

Cell cycle: molecular targets for diagnosis and therapy: tumor suppressor genes and cell cycle progression in cancer.

A Giordano1, Y M Rustum, C E Wenner.   

Abstract

A significant portion of published literature is dedicated to describing the cloning and the characterization of proteins involved in the progression of the cell cycle, which govern cell growth both in cancer and normal ontogenesis. With this abundance of information, the cascading pathways of molecular events that occur in the cell cycle are proving to be exceedingly complicated. The purpose of this conference was to attract the leading clinical and basic science investigators in the growth control field with a final goal to determine how this current wealth of knowledge can be used to impact upon patient care and management by the design of novel adjuvant therapeutics specifically targeted at tumor cells and the identification of molecular diagnostic and/or prognostic markers in an efficient and cost effective manner.

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Year:  1998        PMID: 9632102     DOI: 10.1002/(sici)1097-4644(19980701)70:1<1::aid-jcb1>3.0.co;2-t

Source DB:  PubMed          Journal:  J Cell Biochem        ISSN: 0730-2312            Impact factor:   4.429


  2 in total

1.  CASZ1 inhibits cell cycle progression in neuroblastoma by restoring pRb activity.

Authors:  Zhihui Liu; Julieann Rader; Stanley He; Tanya Phung; Carol J Thiele
Journal:  Cell Cycle       Date:  2013-07-15       Impact factor: 4.534

2.  Nimotuzumab prolongs survival in patients with malignant gliomas: A phase I/II clinical study of concomitant radiochemotherapy with or without nimotuzumab.

Authors:  Jidong Hong; Yuping Peng; Yuping Liao; Wuzhong Jiang; Rui Wei; Lei Huo; Zaide Han; Chaojun Duan; Meizuo Zhong
Journal:  Exp Ther Med       Date:  2012-04-19       Impact factor: 2.447

  2 in total

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