Literature DB >> 9631649

Eukaryotic DNA topoisomerase II beta.

C A Austin1, K L Marsh.   

Abstract

Type II DNA topoisomerase activity is required to change DNA topology. It is important in the relaxation of DNA supercoils generated by cellular processes, such as transcription and replication, and it is essential for the condensation of chromosomes and their segregation during mitosis. In mammals this activity is derived from at least two isoforms, termed DNA topoisomerase II alpha and beta. The alpha isoform is involved in chromosome condensation and segregation, whereas the role of the beta isoform is not yet clear. DNA topoisomerase II beta was first reported in 1987. Here we review the research on DNA topoisomerase II beta over the last 10 years.

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Year:  1998        PMID： 9631649     DOI： 10.1002/(SICI)1521-1878(199803)20:3<215::AID-BIES5>3.0.CO;2-Q

Source DB:  PubMed          Journal:  Bioessays        ISSN： 0265-9247            Impact factor:   4.345


  88 in total

1.  Aberrant lamination in the cerebral cortex of mouse embryos lacking DNA topoisomerase IIbeta.

Authors:  Yi Lisa Lyu; James C Wang
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-28       Impact factor: 11.205

Review 2.  DNA transcription and repair: a confluence.

Authors:  Robb E Moses; Bert W O'Malley
Journal:  J Biol Chem       Date:  2012-05-17       Impact factor: 5.157

3.  Impact of the C-terminal domain of topoisomerase IIalpha on the DNA cleavage activity of the human enzyme.

Authors:  Jennifer S Dickey; Neil Osheroff
Journal:  Biochemistry       Date:  2005-08-30       Impact factor: 3.162

4.  The geometry of DNA supercoils modulates topoisomerase-mediated DNA cleavage and enzyme response to anticancer drugs.

Authors:  A Kathleen McClendon; Neil Osheroff
Journal:  Biochemistry       Date:  2006-03-07       Impact factor: 3.162

5.  Epstein-Barr virus BGLF4 kinase induces premature chromosome condensation through activation of condensin and topoisomerase II.

Authors:  Chung-Pei Lee; Jen-Yang Chen; Jiin-Tarng Wang; Keiji Kimura; Ai Takemoto; Chih-Chung Lu; Mei-Ru Chen
Journal:  J Virol       Date:  2007-03-14       Impact factor: 5.103

6.  Decondensing the protamine domain for transcription.

Authors:  Rui Pires Martins; Stephen A Krawetz
Journal:  Proc Natl Acad Sci U S A       Date:  2007-05-01       Impact factor: 11.205

7.  Suppression of topoisomerase IIalpha expression and function in human cells decreases chromosomal radiosensitivity.

Authors:  Samantha Y A Terry; Andrew C Riches; Peter E Bryant
Journal:  Mutat Res       Date:  2009-02-04       Impact factor: 2.433

8.  DNA Topology and Topoisomerases: Teaching a "Knotty" Subject.

Authors:  Joseph E Deweese; Michael A Osheroff; Neil Osheroff
Journal:  Biochem Mol Biol Educ       Date:  2008       Impact factor: 1.160

Review 9.  DNA topoisomerase II and its growing repertoire of biological functions.

Authors:  John L Nitiss
Journal:  Nat Rev Cancer       Date:  2009-04-20       Impact factor: 60.716

10.  Molecular characterization of a nuclear topoisomerase II from Nicotiana tabacum that functionally complements a temperature-sensitive topoisomerase II yeast mutant.

Authors:  B N Singh; Yashwanti Mudgil; S K Sopory; M K Reddy
Journal:  Plant Mol Biol       Date:  2003-07       Impact factor: 4.076
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