| Literature DB >> 9630598 |
M S Oitzl1, M Fluttert, E R de Kloet.
Abstract
Corticosteroids can facilitate or impair learning and memory processes. We found that the glucocorticoid receptor antagonist RU38486 injected locally into the dorsal hippocampus dose-dependently improved the performance of male Wistar rats in the water maze 24 h after treatment. This observation suggests a discrete specificity of hippocampal glucocorticoid receptors in facilitation of memory. Copyright 1998 Elsevier Science B.V. All rights reserved.Entities:
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Year: 1998 PMID： 9630598 DOI： 10.1016/s0006-8993(98)00387-4
Source DB: PubMed Journal: Brain Res ISSN： 0006-8993 Impact factor: 3.252