Literature DB >> 9630304

Immunoglobulin G crystalline keratopathy associated with monoclonal gammopathy.

K Hutchinson1, M Dal Pra, A Apel.   

Abstract

PURPOSE: Two cases of corneal crystal deposition are reported, both caused by a benign monoclonal gammopathy
METHODS: Similar corneal pathology is identified in these two patients, both of whom presented with visual acuities of 6/6 or better Consideration of possible causes involved biochemical and haematological testing and assessment.
RESULTS: Potential for malignant transformation of monoclonal gammopathy was recognized, hence the need for ongoing haematological follow-up.
CONCLUSION: Corneal crystals may be the initial presentation in a patient with monoclonal gammopathy, a rare, but significant, clinical finding.

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Year:  1998        PMID: 9630304     DOI: 10.1111/j.1442-9071.1998.tb01539.x

Source DB:  PubMed          Journal:  Aust N Z J Ophthalmol        ISSN: 0814-9763


  3 in total

1.  The Hematologic Definition of Monoclonal Gammopathy of Undetermined Significance in Relation to Paraproteinemic Keratopathy (An American Ophthalmological Society Thesis).

Authors:  Walter Lisch; Joanna Wasielica-Poslednik; Tero Kivelä; Ursula Schlötzer-Schrehardt; Jens M Rohrbach; Walter Sekundo; Uwe Pleyer; Christina Lisch; Alexander Desuki; Heidi Rossmann; Jayne S Weiss
Journal:  Trans Am Ophthalmol Soc       Date:  2016-08

2.  Localized conjunctival extra-nodal marginal zone B cell lymphoma with presumed Paraproteinic Crystalline Keratopathy.

Authors:  Thaer S Alomar; Khalid Mahmood; Simon O'Connor; Keith Robson; Harminder S Dua
Journal:  Int Ophthalmol       Date:  2013-01-30       Impact factor: 2.031

3.  In vivo confocal microscopy of verticillata-like paraproteinemic keratopathy in a patient with monoclonal gammopathy of uncertain significance evolving into smoldering multiple myeloma.

Authors:  Chiara Chierego; Tommaso Merz; Adriano Fasolo; Neil Lagali; Emilio Pedrotti
Journal:  Am J Ophthalmol Case Rep       Date:  2019-06-29
  3 in total

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