Literature DB >> 9627533

Torsade de pointes with sotalol overdose treated successfully with lidocaine.

T L Assimes1, I Malcolm.   

Abstract

Torsade de pointes is a polymorphic ventricular tachyarrhythmia associated with a long QT interval. The prognosis is excellent if torsade is recognized early. In the acquired long QT syndrome, measures should be taken quickly to identify and correct all predisposing conditions and to treat or prevent torsade. Established treatments of acquired torsade are magnesium bolus, electrolyte replacement, isoproterenol infusion and cardiac pacing. Sotalol overdose causing torsade is reported in which lidocaine appears to have suppressed an episode of torsade as well as prevented further episodes. Current understanding of the electrophysiological mechanisms of torsade and lidocaine, a review of the literature and the author's experience indicate that lidocaine is a potentially useful therapy in torsade.

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Year:  1998        PMID: 9627533

Source DB:  PubMed          Journal:  Can J Cardiol        ISSN: 0828-282X            Impact factor:   5.223


  3 in total

Review 1.  Pharmacological treatment of acquired QT prolongation and torsades de pointes.

Authors:  Simon H L Thomas; Elijah R Behr
Journal:  Br J Clin Pharmacol       Date:  2015-10-26       Impact factor: 4.335

2.  Tedisamil and lidocaine enhance each other's antiarrhythmic activity against ischaemia-induced arrhythmias in rats.

Authors:  Guilda Sarraf; Terrance D Barrett; Michael J A Walker
Journal:  Br J Pharmacol       Date:  2003-08       Impact factor: 8.739

3.  Abiraterone-induced refractory hypokalaemia and torsades de pointes in a patient with metastatic castration-resistant prostate carcinoma: a case report.

Authors:  Mariam Riad; Jeffery Scott Allison; Shahla Nayyal; AbdulWahab Hritani
Journal:  Eur Heart J Case Rep       Date:  2021-11-16
  3 in total

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