Literature DB >> 9627108

Involvement of MMP-1 and MMP-3 in collagen degradation induced by IL-1 in rabbit cartilage explant culture.

S Saito1, M Katoh, M Masumoto, S Matsumoto, Y Masuho.   

Abstract

To determine whether matrix metalloproteinase-1 (MMP-1) or MMP-3 is involved in cartilage collagen degradation, polyclonal antibodies were separately raised against MMP-1 and MMP-3 and their effects on collagen degradation were assessed in rabbit cartilage explant culture. We found that anti-MMP-1 antibodies completely inhibited collagen degradation induced by the combination of interleukin-1 (IL-1) and plasminogen. Anti-MMP-3 antibodies showed 40% inhibition at maximum concentration. These results indicate that MMP-1, and possibly MMP-3, are involved in collagen degradation in cartilage explant culture.

Entities:  

Mesh：

Substances：

Year:  1998        PMID： 9627108     DOI： 10.1016/s0024-3205(98)00181-7

Source DB:  PubMed          Journal:  Life Sci        ISSN： 0024-3205            Impact factor:   5.037


  9 in total

1.  Chondrogenic Gene Expression Differences between Chondrocytes from Osteoarthritic and Non-OA Trauma Joints in a 3D Collagen Type I Hydrogel.

Authors:  Vivek Jeyakumar; Florian Halbwirth; Eugenia Niculescu-Morzsa; Christoph Bauer; Hannes Zwickl; Daniela Kern; Stefan Nehrer
Journal:  Cartilage       Date:  2016-07-07       Impact factor: 4.634

2.  Cyclic tensile strain suppresses catabolic effects of interleukin-1beta in fibrochondrocytes from the temporomandibular joint.

Authors:  S Agarwal; P Long; R Gassner; N P Piesco; M J Buckley
Journal:  Arthritis Rheum       Date:  2001-03

3.  Cyclic tensile strain acts as an antagonist of IL-1 beta actions in chondrocytes.

Authors:  Z Xu; M J Buckley; C H Evans; S Agarwal
Journal:  J Immunol       Date:  2000-07-01       Impact factor: 5.422

4.  Potential of Raloxifene in reversing osteoarthritis-like alterations in rat chondrocytes: an in vitro model study.

Authors:  Aysegul Kavas; Seda Tuncay Cagatay; Sreeparna Banerjee; Dilek Keskin; Aysen Tezcaner
Journal:  J Biosci       Date:  2013-03       Impact factor: 1.826

5.  Adenoviral gene transfer of interleukin-1 in combination with oncostatin M induces significant joint damage in a murine model.

Authors:  Andrew D Rowan; Wang Hui; Tim E Cawston; Carl D Richards
Journal:  Am J Pathol       Date:  2003-06       Impact factor: 4.307

6.  Are there any differences among non-steroidal anti-inflammatory drugs? Focus on nimesulide.

Authors:  Franco Dallegri; Luciano Ottonello
Journal:  Clin Drug Investig       Date:  2007-12       Impact factor: 2.859

7.  Active compound of Zingiber cassumunar Roxb. down-regulates the expression of genes involved in joint erosion in a human synovial fibroblast cell line.

Authors:  Rujirek Chaiwongsa; Siriwan Ongchai; Phorani Boonsing; Prachya Kongtawelert; Ampai Panthong; Vichai Reutrakul
Journal:  Afr J Tradit Complement Altern Med       Date:  2012-10-01

8.  Combining stretching and gallic acid to decrease inflammation indices and promote extracellular matrix production in osteoarthritic human articular chondrocytes.

Authors:  Haneen A Abusharkh; Olivia M Reynolds; Juana Mendenhall; Bulent A Gozen; Edwin Tingstad; Vincent Idone; Nehal I Abu-Lail; Bernard J Van Wie
Journal:  Exp Cell Res       Date:  2021-09-24       Impact factor: 4.145

9.  Magnetic Stimulation Drives Macrophage Polarization in Cell to-Cell Communication with IL-1β Primed Tendon Cells.

Authors:  Adriana Vinhas; Ana F Almeida; Ana I Gonçalves; Márcia T Rodrigues; Manuela E Gomes
Journal:  Int J Mol Sci       Date:  2020-07-30       Impact factor: 5.923
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.