Literature DB >> 9627066

Should a cancer patient be resuscitated following an in-hospital cardiac arrest?

J Varon1, G L Walsh, P E Marik, R E Fromm.   

Abstract

OBJECTIVE: Previous reports from general hospitals and cancer centers have identified the presence of malignancy as a poor prognostic indicator for successful cardiopulmonary resuscitation (CPR) for an in-hospital cardiac arrest. The purpose of this study was to evaluate the initial success of CPR as determined by return of spontaneous circulation (ROSC), patient survival to hospital discharge, and 1-year survival of this group as compared to previous studies in non-oncological centers. In addition, the charges incurred in caring for these patients were analyzed.
MATERIALS AND METHODS: All cardiac arrests occurring between 1 January 1993 and 31 December 1994 were identified from a centralized morbidity and mortality database and reviewed retrospectively. Cardiac arrest was defined as the absence of a palpable pulse and initiation of CPR. Patients suffering pure respiratory arrest or shock without loss of pulse were excluded. Age, gender, primary site of malignancy, initial and ultimate outcome, including Zubrod's functional status (ZFS), and total hospital charges following cardiac arrest were recorded. Computerized billing records were used to tabulate total charges.
RESULTS: 83 cardiac arrests occurred during the study period (42 women, 41 men). Mean age was 56.2 years. Forty-two percent of the patients had hematologic malignancies, 19% lung, 15% gastrointestinal, 5% head and neck cancers and 19% other malignancies. Sixty-six percent of the patients had ROSC. Only eight (9.6%) patients survived to hospital discharge: three died within 6 weeks under hospice care, two died within 6 months of discharge and only three (3.6%) patients survived to 1 year. Functional status follow-up of these three patients revealed two with ZFS 1 and one with ZFS 2. Total hospital charges for these 83 patients were US$ 2,959,740.
CONCLUSIONS: Although ROSC after cardiac arrest in our patients was better than that reported for most series in general hospitals, their ultimate survival and hospital discharge was extremely poor.

Entities:  

Keywords:  Death and Euthanasia; Empirical Approach

Mesh:

Year:  1998        PMID: 9627066     DOI: 10.1016/s0300-9572(98)00015-x

Source DB:  PubMed          Journal:  Resuscitation        ISSN: 0300-9572            Impact factor:   5.262


  10 in total

1.  Doctors should not discuss resuscitation with terminally ill patients: FOR.

Authors:  Charlotte Manisty; Jonathan Waxman
Journal:  BMJ       Date:  2003-09-13

Review 2.  Do-not-resuscitate orders in cancer patients: a review of literature.

Authors:  Aart Osinski; Gerard Vreugdenhil; Jan de Koning; Johannes G van der Hoeven
Journal:  Support Care Cancer       Date:  2016-10-22       Impact factor: 3.603

3.  In pursuit of an artful death: discussion of resuscitation status on an inpatient radiation oncology service.

Authors:  Alysa Fairchild; Karie-Lynn Kelly; Alex Balogh
Journal:  Support Care Cancer       Date:  2005-04-22       Impact factor: 3.603

Review 4.  A critical review of the factors leading to cardiopulmonary resuscitation as the default position of hospitalized patients in the USA regardless of severity of illness.

Authors:  Loukas Georgiou; Anastasios Georgiou
Journal:  Int J Emerg Med       Date:  2019-03-13

5.  Goals-of-care discussions.

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Journal:  J Community Support Oncol       Date:  2017 Jul-Aug

6.  [Emergency medical treatment of palliative care patients at the end of life: regulatory emergency medical care framework--a case control investigation of medical intervention and advance directives].

Authors:  C H R Wiese; G Duttge; A K Weber; Y A Zausig; D Ruppert; G G Hanekop; B M Graf
Journal:  Anaesthesist       Date:  2009-11       Impact factor: 1.041

7.  Outcome of stage IV cancer patients receiving in-hospital cardiopulmonary resuscitation: a population-based cohort study.

Authors:  Meng-Rui Lee; Kai-Lun Yu; Hung-Yang Kuo; Tsung-Hao Liu; Jen-Chung Ko; Jaw-Shiun Tsai; Jann-Yuan Wang
Journal:  Sci Rep       Date:  2019-07-01       Impact factor: 4.379

8.  Short- and Long-Term Outcomes of Hematologic Malignancy Patients After Cardiopulmonary Resuscitation: Experience of a Large Oncology Center.

Authors:  Mary Lou Warren; Virginia V Schneider; Yun Qing; Lei Feng; Jeanne Y Campbell; Jason W Myers; Marian Von-Maszewski; Cristina Gutierrez
Journal:  J Adv Pract Oncol       Date:  2021-09-01

9.  Predictors of cardiopulmonary arrest outcome in a comprehensive cancer center intensive care unit.

Authors:  Faisal A Khasawneh; Mahmoud T Kamel; Mohammad I Abu-Zaid
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2013-03-20       Impact factor: 2.953

10.  Trends in In-Hospital Cardiopulmonary Resuscitation from 2010 through 2019: A Nationwide Cohort Study in South Korea.

Authors:  Tak Kyu Oh; You Hwan Jo; In-Ae Song
Journal:  J Pers Med       Date:  2022-03-01
  10 in total

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