Literature DB >> 9624504

Characterization of the 6'-N-aminoglycoside acetyltransferase gene aac(6')-Iq from the integron of a natural multiresistance plasmid.

D Centrón1, P H Roy.   

Abstract

The nucleotide sequence of a newly identified amikacin resistance gene, aac(6')-Iq (551 bp), is reported. It has 68.4 and 94.4% homology with the aac(6')-Ia gene and the recently described aac(6')-Ip gene, respectively. Analysis of its flanking sequences indicated that it is in the first cassette of a class I integron and has an attC site (59-base element) 108 bp in length.

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Year:  1998        PMID： 9624504      PMCID： PMC105632     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  17 in total

1.  Primary structure of an aminoglycoside 6'-N-acetyltransferase AAC(6')-4, fused in vivo with the signal peptide of the Tn3-encoded beta-lactamase.

Authors:  G Tran van Nhieu; E Collatz
Journal:  J Bacteriol       Date:  1987-12       Impact factor: 3.490

2.  Tn402: a new transposable element determining trimethoprim resistance that inserts in bacteriophage lambda.

Authors:  J A Shapiro; P Sporn
Journal:  J Bacteriol       Date:  1977-03       Impact factor: 3.490

3.  Genetic organization of antibiotic resistance genes (aac(6')-Ib, aadA, and oxa9) in the multiresistance transposon Tn1331.

Authors:  M E Tolmasky; J H Crosa
Journal:  Plasmid       Date:  1993-01       Impact factor: 3.466

4.  Functional analysis of the 5' regulatory region and the UUG translation initiation codon of the Arthrobacter oxidans 6-hydroxy-D-nicotine oxidase gene.

Authors:  L Mauch; V Bichler; R Brandsch
Journal:  Mol Gen Genet       Date:  1990-05

5.  Diversity and relative strength of tandem promoters for the antibiotic-resistance genes of several integrons.

Authors:  C Lévesque; S Brassard; J Lapointe; P H Roy
Journal:  Gene       Date:  1994-05-03       Impact factor: 3.688

6.  Characterization of the chromosomal aac(6')-Ii gene specific for Enterococcus faecium.

Authors:  Y Costa; M Galimand; R Leclercq; J Duval; P Courvalin
Journal:  Antimicrob Agents Chemother       Date:  1993-09       Impact factor: 5.191

7.  Characterisation of specific and secondary recombination sites recognised by the integron DNA integrase.

Authors:  G D Recchia; H W Stokes; R M Hall
Journal:  Nucleic Acids Res       Date:  1994-06-11       Impact factor: 16.971

8.  The emergence of resistance to amikacin in Serratia marcescens isolates from patients with nosocomial infection.

Authors:  D C García; M Catalano; S Piñeiro; M Woloj; S Kaufman; D O Sordelli
Journal:  Int J Antimicrob Agents       Date:  1996-08       Impact factor: 5.283

Review 9.  Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes.

Authors:  K J Shaw; P N Rather; R S Hare; G H Miller
Journal:  Microbiol Rev       Date:  1993-03

10.  Characterization of In0 of Pseudomonas aeruginosa plasmid pVS1, an ancestor of integrons of multiresistance plasmids and transposons of gram-negative bacteria.

Authors:  L Bissonnette; P H Roy
Journal:  J Bacteriol       Date:  1992-02       Impact factor: 3.490
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  8 in total

1.  Systematic analysis of a conserved region of the aminoglycoside 6'-N-acetyltransferase type Ib.

Authors:  A Shmara; N Weinsetel; K J Dery; R Chavideh; M E Tolmasky
Journal:  Antimicrob Agents Chemother       Date:  2001-12       Impact factor: 5.191

2.  A novel gene cassette, aacA43, in a plasmid-borne class 1 integron.

Authors:  Sally R Partridge; Lee C Thomas; Andrew N Ginn; Agnieszka M Wiklendt; Pierre Kyme; Jonathan R Iredell
Journal:  Antimicrob Agents Chemother       Date:  2011-03-21       Impact factor: 5.191

3.  Aminoglycoside resistance genes aph(2")-Ib and aac(6')-Im detected together in strains of both Escherichia coli and Enterococcus faecium.

Authors:  J W Chow; V Kak; I You; S J Kao; J Petrin; D B Clewell; S A Lerner; G H Miller; K J Shaw
Journal:  Antimicrob Agents Chemother       Date:  2001-10       Impact factor: 5.191

Review 4.  Aminoglycoside modifying enzymes.

Authors:  Maria S Ramirez; Marcelo E Tolmasky
Journal:  Drug Resist Updat       Date:  2010-09-15       Impact factor: 18.500

5.  Multidrug-resistant Pseudomonas aeruginosa strain that caused an outbreak in a neurosurgery ward and its aac(6')-Iae gene cassette encoding a novel aminoglycoside acetyltransferase.

Authors:  Jun-ichiro Sekiguchi; Tsukasa Asagi; Tohru Miyoshi-Akiyama; Tomoko Fujino; Intetsu Kobayashi; Koji Morita; Yoshihiro Kikuchi; Tadatoshi Kuratsuji; Teruo Kirikae
Journal:  Antimicrob Agents Chemother       Date:  2005-09       Impact factor: 5.191

6.  novel 6'-n-aminoglycoside acetyltransferase AAC(6')-Iaj from a clinical isolate of Pseudomonas aeruginosa.

Authors:  Tatsuya Tada; Tohru Miyoshi-Akiyama; Kayo Shimada; Masahiro Shimojima; Teruo Kirikae
Journal:  Antimicrob Agents Chemother       Date:  2012-10-15       Impact factor: 5.191

Review 7.  Versatility of aminoglycosides and prospects for their future.

Authors:  Sergei B Vakulenko; Shahriar Mobashery
Journal:  Clin Microbiol Rev       Date:  2003-07       Impact factor: 26.132

8.  AAC(6')-Iaf, a novel aminoglycoside 6'-N-acetyltransferase from multidrug-resistant Pseudomonas aeruginosa clinical isolates.

Authors:  Tomoe Kitao; Tohru Miyoshi-Akiyama; Teruo Kirikae
Journal:  Antimicrob Agents Chemother       Date:  2009-04-06       Impact factor: 5.191
  8 in total

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