Literature DB >> 9621420

Synthesis and antimicrobial activity of pyridines bearing thiazoline and thiazolidinone moieties.

H Y Hassan1, N A el-Koussi, Z S Farghaly.   

Abstract

Two series of new pyridines bearing thiazoline (3a--n) and thiazolidinone (5a--e) moieties were prepared via the cyclization of the corresponding substituted pyridyl thiourea (2a--g) with an appropriately substituted phenacyl bromide or chloroacetic acid, respectively. The antimicrobial activity was determined for representative compounds and most of them showed moderate activity against Gram-positive bacteria.

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Year:  1998        PMID： 9621420     DOI： 10.1248/cpb.46.863

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  3 in total

1.  Synthesis, Antimicrobial, and Anti-Proliferative Activities of Novel 4-(Adamantan-1-yl)-1-arylidene-3-thiosemicarbazides, 4-Arylmethyl N'-(Adamantan-1-yl)piperidine-1-carbothioimidates, and Related Derivatives.

Authors:  Aamal A Al-Mutairi; Monirah A Al-Alshaikh; Fatmah A M Al-Omary; Hanan M Hassan; Areej M El-Mahdy; Ali A El-Emam
Journal:  Molecules       Date:  2019-11-26       Impact factor: 4.411

2.  Probing the Effect of Halogen Substituents (Br, Cl, and F) on the Non-covalent Interactions in 1-(Adamantan-1-yl)-3-arylthiourea Derivatives: A Theoretical Study.

Authors:  Lamya H Al-Wahaibi; Divya Sri Grandhi; Samar S Tawfik; Nora H Al-Shaalan; Mohammed A Elmorsy; Ali A El-Emam; M Judith Percino; Subbiah Thamotharan
Journal:  ACS Omega       Date:  2021-02-10

3.  Exploring 2-Tetradecanoylimino-3-aryl-4-methyl-1,3-thiazolines Derivatives as Alkaline Phosphatase Inhibitors: Biochemical Evaluation and Computational Analysis.

Authors:  Aftab Ahmed; Sajid-Ur Rehman; Syeda Abida Ejaz; Aamer Saeed; Rabail Ujan; Pervaiz Ali Channar; Khalida Mahar; Reshma Sahito; Sarah M Albogami; Qamar Abbas; Mohammed Alorabi; Michel De Waard; Gaber El-Saber Batiha
Journal:  Molecules       Date:  2022-10-10       Impact factor: 4.927
  3 in total

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