Literature DB >> 9621409

Further investigation of phenanthroindolizidine alkaloids from Tylophora tanakae.

F Abe1, M Hirokawa, T Yamauchi, K Honda, N Hayashi, M Ishii, S Imagawa, M Iwahana.   

Abstract

In addition to ten alkaloids previously described, we have isolated two alkaloid N-oxides from Tylophora tanakae MAXIM. (Asclepiadaceae). Further, the polar fraction of the leaves and caules of this plant cultivated in a farm afforded two new polar alkaloids. The structures of the four products were determined. The relation between the structure and cytotoxic activity of this group of alkaloids is discussed.

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Year:  1998        PMID: 9621409     DOI: 10.1248/cpb.46.767

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  2 in total

1.  In vitro cytotoxic screening of selected Saudi medicinal plants.

Authors:  Hussein Almehdar; Hossam M Abdallah; Abdel-Moneim M Osman; Essam A Abdel-Sattar
Journal:  J Nat Med       Date:  2011-09-28       Impact factor: 2.343

2.  Screening of promising chemotherapeutic candidates from plants against human adult T-cell leukemia/lymphoma (IV): phenanthroindolizidine alkaloids from Tylophora tanakae leaves.

Authors:  Daisuke Nakano; Kenji Ishitsuka; Mizuki Ikeda; Ryota Tsuchihashi; Masafumi Okawa; Hikaru Okabe; Kazuo Tamura; Junei Kinjo
Journal:  J Nat Med       Date:  2015-04-04       Impact factor: 2.343

  2 in total

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