Literature DB >> 9619115

Torilin, a sesquiterpene from Torilis japonica, reverses multidrug-resistance in cancer cells.

S E Kim1, Y H Kim, Y C Kim, J J Lee.   

Abstract

A sesquiterpene compound reversing multidrug-resistance in cancer cells was isolated from the fruits of Torilis japonica and the structure was identified as torilin. Torilin potentiated the cytotoxicities of adriamycin, vinblastine, taxol and colchicine against multidrug-resistant KB-V1 and MCF7/ADR cells.

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Year:  1998        PMID： 9619115     DOI： 10.1055/s-2006-957445

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  2 in total

1.  GC/MS analysis of high-performance liquid chromatography fractions from Sophora flavescens and Torilis japonica extracts and their in vitro anti-neosporal effects on Neospora caninum.

Authors:  Hun-Su Seo; Kyoung Hee Kim; Dae-Yong Kim; Bong-Kyun Park; Nam-Shik Shin; Jae-Hoon Kim; Heejeong Youn
Journal:  J Vet Sci       Date:  2013-06-30       Impact factor: 1.672

2.  Torilin Inhibits Inflammation by Limiting TAK1-Mediated MAP Kinase and NF-κB Activation.

Authors:  Mehari Endale; Tae-Hwan Kim; Yi-Seong Kwak; Na-Mi Kim; Seung-Hyung Kim; Jae Youl Cho; Bong-Sik Yun; Man-Hee Rhee
Journal:  Mediators Inflamm       Date:  2017-02-20       Impact factor: 4.711
  2 in total

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